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http://dx.doi.org/10.1136/jmg.38.1.61 | DOI Listing |
Sci Rep
January 2025
Laboratório de Planejamento e Desenvolvimento de Fármacos, Instituto de Ciências Exatas e Naturais, Universidade Federal do Pará, Belém, Pará, 66075-110, Brazil.
Plastic poses a significant environmental impact due to its chemical resilience, leading to prolonged and degradation times and resulting in widespread adverse effects on global flora and fauna. Cutinases are essential enzymes in the biodegradation process of synthetic polymers like polyethylene terephthalate (PET), which recognized organisms can break down. Here, we used molecular dynamics and binding free energy calculations to explore the interaction of nine synthetic polymers, including PET, with Cutinase from Fusarium oxysporum (FoCut).
View Article and Find Full Text PDFJ Parasitol
January 2025
Zoology, School of Biological Sciences, Southern Illinois University, Carbondale, Illinois 62901-6501.
The present work includes the description of Gyrinicola pilyolcatzin n. sp. (Nematoda: Oxyurida) collected from the large intestine of tadpoles of the Montezuma frog, Rana montezumae.
View Article and Find Full Text PDFVirus Evol
December 2024
Department of Epidemiology and Population Health, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305, United States.
Despite the increasing burden of dengue in Kenya and Africa, the introduction and expansion of the virus in the region remain poorly understood. The objective of this study is to examine the genetic diversity and evolutionary histories of dengue virus (DENV) serotypes 1 and 3 in Kenya and contextualize their circulation within circulation dynamics in the broader African region. Viral RNA was extracted from samples collected from a cohort of febrile patients recruited at clinical sites in Kenya from 2013 to 2022.
View Article and Find Full Text PDFFront Microbiol
January 2025
Shanghai Engineering Center of Hadal Science and Technology, College of Marine Sciences, Shanghai Ocean University, Shanghai, China.
Strain LCG007, isolated from Lu Chao Harbor's intertidal water, phylogenetically represents a novel genus within the family Rhodobacteraceae. Metabolically, it possesses a wide array of amino acid metabolic genes that enable it to thrive on both amino acids or peptides. Also, it could hydrolyze peptides containing D-amino acids, highlighting its potential role in the cycling of refractory organic matter.
View Article and Find Full Text PDFbioRxiv
January 2025
APC Microbiome Ireland, University College Cork, Co. Cork, T12 YT20, Ireland.
Bacteriophage research has experienced a renaissance in recent years, owing to their therapeutic potential and versatility in biotechnology, particularly in combating antibiotic resistant-bacteria along the farm-to-fork continuum. However, certain pathogens remain underexplored as targets for phage therapy, including the zoonotic pathogen which causes infections in pigs and humans. Despite global efforts, the genome of only one infective phage has been described.
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