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Evaluation of Xanthine Oxidase Inhibitors Febuxostat and Allopurinol on Kidney Dysfunction and Histological Damage in Two-Kidney, One-Clip (2K1C) Rats.
Scientifica (Cairo)
January 2025
Department of Pharmaceutical Sciences, North South University, Dhaka, Bangladesh.
In chronic kidney disease (CKD), hyperuricemia is a common phenomenon, presumably due to reduced renal clearance of uric acid. This study investigated the effect of xanthine oxidase (XO) inhibitors allopurinol and febuxostat to prevent oxidative stress in the kidney of two-kidney, one-clip (2K1C) rats. In this investigation, 2K1C rats were used as an experimental animal model for kidney dysfunction.
View Article and Find Full Text PDFDomestic water consumptions and associated factors in rural household of Harari region, Eastern Ethiopia; A cross sectional study.
Front Public Health
January 2025
Department of Environmental Health, College of Health and Medical Sciences, Haramaya University, Harar, Ethiopia.
Background: Sustainable rural water supply management requires accurate estimations of water consumption and understanding factors influencing consumption. Climate change exacerbates challenges, especially in developing countries with high poverty and limited access to clean water. Ethiopia has the lowest municipal water supply in Africa.
View Article and Find Full Text PDFLignin and Peptide Promote the Abundance and Activity of Arsenic Methylation Microbes in Paddy Soils.
Environ Sci Technol
January 2025
Zhejiang Provincial Key Laboratory of Agricultural Resources and Environment, College of Environmental and Resource Sciences, Zhejiang University, Hangzhou 310058, China.
Rice physiological straighthead disease is induced by microbially mediated arsenic methylation and usually regionally distributed in paddy soils. However, the biogeochemical mechanism underlying the geographic distribution of microbial communities harboring methylating genes () remains unclear. Herein, we revealed significant ( = 0.
View Article and Find Full Text PDFMachine learning models for water safety enhancement.
Sci Rep
January 2025
Faculty of Industrial and Systems Engineering, Tarbiat Modares University, Tehran, 4117-13114, Iran.
Humans encounter both natural and artificial radiation sources, including cosmic rays, primordial radionuclides, and radiation generated by human activities. These radionuclides can infiltrate the human body through various pathways, potentially leading to cancer and genetic mutations. A study was conducted using random sampling to assess the concentrations of radioactive isotopes and heavy metals in mineral water from Iran, consumable at Arak City.
View Article and Find Full Text PDFPesticide transformation products: a potential new source of interest for drinking water.
Environ Sci Pollut Res Int
January 2025
ANSES, Nancy Laboratory for Hydrology, Water Chemistry Department, 40 Rue Lionnois, 54000, Nancy, France.
Pesticide transformation products (TPs) are frequently quantified in aquatic systems, including surface and groundwater. They often present higher polarity than parent compounds, are less volatile and less biodegradable and are therefore more mobile and persistent. These properties make them compounds of main interest in water resources and drinking water.
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