Purpose: Quality standards for restorations recently have been defined in Switzerland. Amalgam substitutes must meet restoration Grade 2 requirements (i.e., pulp and dental hard substance must be preserved, and both form and function of the tooth have to be reconstituted). The pertinent operative technique has to be simple and amalgam-like. A minimum service life of 8 years is required. This in vitro study investigated the clinical potential of several amalgam substitutes, taking into account the operative requirements, the defined restorative guidelines, and the required service life.
Materials And Methods: Potential amalgam substitutes evaluated in this study included compomers (Compoglass, Dyract, Dyract AP, Elan, F 2000) and resin-based composites (Alert, Ariston, Definite, Nulite, Solitaire, Surefil). The composites Adaptic and Tetric Cream, using a simplified placement technique, were tested as negative and positive controls, respectively. Marginal adaptation and wear properties were measured in vitro in mixed Class II cavities. Relative radiopacity was measured in terms of millimeters of equivalent aluminum.
Results: All compomers showed a radiopacity of 2.5 mm or more aluminum. Only Dyract AP and Elan were more wear resistant than amalgam. After stressing, the percentage of continuous margin was at best 31% overall and 17% in dentin only. Among resin-based composites, the minimum requirements of radiopacity were fulfilled only by Alert, Surefil, and Tetric. Only Definite, Surefil, Solitaire, and Tetric exhibited wear resistance greater than amalgam. After stressing, the best marginal qualities were 41% continuous margin overall, and 8% in dentin only.
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Am J Transl Res
August 2023
Department of Physiology and Cell Biology, The Ohio State University Wexner Medical Center Columbus, Ohio 43210, USA.
Drug repurposing, also known as drug repositioning, entails the application of pre-approved or formerly assessed drugs having potentially functional therapeutic amalgams for curing various disorders or disease conditions distinctive from their original remedial indication. It has surfaced as a substitute for the development of drugs for treating cancer, cardiovascular diseases, neurodegenerative disorders, and various infectious diseases like Covid-19. Although the earlier lines of findings in this area were serendipitous, recent advancements are based on patient centered approaches following systematic, translational, drug targeting practices that explore pathophysiological ailment mechanisms.
View Article and Find Full Text PDFEur Oral Res
May 2023
Department of Pedodontics and Preventive Dentistry, Institute of Dental Studies and Technologies,Modinagar, Ghaziabad, Uttar Pradesh,India.
Purpose: The popularity of dental amalgam arises from its excellent long-term performance, ease of use, and low cost. However, there is a concern about the potential adverse health effects arising from exposure to mercury in amalgam. This review article critically discusses the safety of dental amalgam as a restorative material and our preparedness for a mercury-free road ahead.
View Article and Find Full Text PDFInorg Chem
March 2023
Department Chemie, Ludwig-Maximilians-Universität München, 81377 München, Germany.
The two new ternary amalgams KRbHg [ = 0.472(7)] and CsCaHg [ = 0.20(3)] represent two different examples of how to create ternary compounds from binaries by statistical atom substitution.
View Article and Find Full Text PDFEnviron Sci Pollut Res Int
March 2023
Mechanical Engineering Department, NIT Puducherry, Karaikal, Puducherry, India.
The need for non-renewable fuels is steadily decreasing with their ever-increasing cost and air pollution. As a result, renewable fuel such as biofuel is used as a fuel substitute for diesel engines. The effects of magnesia and alumina nanoparticles on the exhaust pollutants and performance of a naturally aspirated, 17.
View Article and Find Full Text PDFInorg Chem
May 2022
School of Molecular Sciences, Arizona State University, Tempe, Arizona 85287, United States.
It was recently discovered that (PDI)Mn (PDI = pyridine diimine) exists as a superposition of low-spin Mn(II) that is supported by a PDI dianion and intermediate-spin Mn(II) that is antiferromagnetically coupled to a triplet PDI dianion, a finding that encouraged the synthesis and electronic structure evaluation of late first row metal variants that feature the same chelate. The addition of PDI to FeBr resulted in bromide dissociation and the formation of [(PDI)FeBr][Br]. Reduction of this precursor using excess sodium amalgam afforded (PDI)Fe, which possesses an Fe(II) center that is supported by a dianionic PDI ligand.
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