We report a case of cerebral deep venous thrombosis that manifested clinically by a pseudobulbar syndrome with major trismus, abnormal movements and static cerebellar syndrome. To our knowledge, only three other cases of deep cerebral venous thrombosis associated with cerebellar or pseudobulbar syndrome have been published since 1985. The relatively good prognosis in our patient could be explained by the partially intact internal cerebral veins as well as use of early anticoagulant therapy. There was a spontaneous hyperdensity of the falx cerebri and the tentorium cerebelli on the brain CT scan, an aspect highly contributive to diagnosis. This hyperdensity of the falx cerebri was found in 19 out of 22 cases of deep venous thrombosis detailed in the literature.
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Zh Nevrol Psikhiatr Im S S Korsakova
January 2025
Pirogov Russian National Research Medical University (Pirogov University), Moscow, Russia.
Locked-in syndrome is a rare neurological disorder. It is characterized by tetraparesis, paralysis of facial and masticatory muscles, anarthria and pseudobulbar syndrome with possible preservation of vertical movements of the eyeballs and blinking, as well as preservation of consciousness. A serious problem with the «locked-in person» syndrome is the inability of the patient to socialize, which causes him to experience no less suffering than from physical limitations.
View Article and Find Full Text PDFPediatr Neurol
February 2025
Department of Pediatrics, St. Francis Hospital Nsambya, Kampala, Uganda; Consultant Pediatric Neurologist, Department of Pediatrics, St. Francis Hospital Nsambya, Kampala, Uganda.
Congenital bilateral perisylvian syndrome (CBPS) is a rare neuronal migration disorder of cortical development characterized by polymicrogyria on magnetic resonance imaging. Features include pseudobulbar palsy, language and speech difficulties, epilepsy, and cognitive deficits. We discuss the management of the case of a five-year-old male with classical features of CBPS.
View Article and Find Full Text PDFPediatr Investig
September 2024
Importance: Viral encephalitis is one of the main causes of the perisylvian syndrome, which can cause damage to children's language-speech, feeding, and swallowing functions. Comprehensive assessment of language-speech and swallowing function and comorbidity research on these children will help children's rehabilitation workers to better understand the disease and strengthen the systematic management of comorbid disorders.
Objective: To describe speech and language pathology and the occurrence of comorbid disorders in children with perisylvian syndrome induced by viral encephalitis.
Front Neurol
September 2024
Department of Biomedical Sciences, College of Veterinary Medicine, University of Missouri, Columbia, MO, United States.
Expert Rev Neurother
November 2024
Center for Translational Cognitive Neuroscience, Veterans Affairs Boston Healthcare System, Boston, MA, USA.
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