This paper describes a novel approach to correct osteotomy deformities of long bones using virtual reality and image processing techniques on personal computers. The discussed method allows to simulate osteotomy corrections by implementing a single cut and a rearrangement of the dissected bone parts. It allows the surgeon to directly control the pre-operative situation and the post-operative result of the simulation by comparing bone-length, angles, and torsion of the bone. In addition, he or she obtains the coordinates and angles of the planned cut relative to anatomical landmarks.
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Front Immunol
January 2025
Department of Botany and Microbiology, College of Science, King Saud University, Riyadh, Saudi Arabia.
Human rhinovirus C (HRV-C) is a significant contributor to respiratory tract infections in children and is implicated in asthma exacerbations across all age groups. Despite its impact, there is currently no licensed vaccine available for HRV-C. Here, we present a novel approach to address this gap by employing immunoinformatics techniques for the design of a multi-epitope-based vaccine against HRV-C.
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January 2025
State Key Laboratory of Respiratory Disease, Guangdong Laboratory of Computational Biomedicine, Center for Cell Lineage Research, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.
Background: Although immunoglobulin (Ig) alleles play a pivotal role in the antibody response to pathogens, research to understand their role in the humoral immune response is still limited.
Methods: We retrieved the germline sequences for the IGHV from the IMGT database to illustrate the amino acid polymorphism present within germline sequences of IGHV genes. We aassembled the sequences of IgM and IgD repertoire from 130 people to investigate the genetic variations in the population.
World J Gastroenterol
January 2025
Department of Oncology Surgery, Cell Therapy and Organ Transplantation, Institute of Biomedicine of Seville, Virgen del Rocio University Hospital, Seville 41013, Spain.
Background: Hepatocellular carcinoma (HCC) is the most common subtype of primary liver cancer with varied incidence and epidemiology worldwide. Sorafenib is still a recommended treatment for a large proportion of patients with advanced HCC. Different patterns of treatment responsiveness have been identified in differentiated hepatoblastoma HepG2 cells and metastatic HCC SNU449 cells.
View Article and Find Full Text PDFDrug Des Devel Ther
January 2025
Foshan Hospital of Traditional Chinese Medicine, Foshan, Guangdong, People's Republic of China.
Background: Dachaihu decoction (DCHD) is a common Chinese medicine formula against sepsis-induced acute lung injury (SALI). PANoptosis is a novel type of programmed cell death. Nevertheless, The mechanisms of DCHD against SALI via anti-PANoptosis remains unknown.
View Article and Find Full Text PDFElectronics (Basel)
October 2024
Department of Electrical and Computer Engineering, Worcester Polytechnic Institute, Worcester, MA 01609, USA.
This paper outlines a design approach for biomedical wireless power transfer systems with a focus on three-coil inductive links for neonatal intensive care unit applications. The relevant literature has been explored to support the design approach, equations, simulation results, and the process of experimental analysis. The paper begins with a brief overview of various power amplifier classes, followed by an in-depth examination of the most common power amplifiers used in biomedical wireless power transfer systems.
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