Correlation between family history of hypertension and haemostatic disorders.

Background: The aim of this study was to evaluate whether a family history of hypertension is associated with haemostatic disorders.

Methods: In 38 normotensive subjects with a family history of hypertension (relatives) and in 46 sex, age and body mass index matched controls with no family history of hypertension, tissue-type plasminogen activator (t-PA), plasminogen activator-inhibitor (PAI-1), D-dimer (DD) and prothrombin fragment 1+2 (F1+2) were evaluated.

Results: The t-PA and PAI-1 observed values were significantly higher than the values detected in the controls.

Conclusions: These data seem to suggest a correlation between family history of hypertension and haemostatic disorders.