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Coronoid height index: a reliable and reproducible technique for quantifying coronoid bone loss in elbow instability.
JSES Int
November 2024
Brighton and Sussex Medical School, Brighton, United Kingdom.
Background: Coronoid fracture size is one important factor in decision-making on surgical vs. nonsurgical management. There is currently no reliable, standardized technique to measure coronoid fracture size or bone loss.
View Article and Find Full Text PDFBackground: Dental caries remains the most prevalent chronic disease worldwide. Hence the importance of detecting and evaluating caries and combining this with additional diagnostic methods to ensure the best treatment. The main objective was to study what is the sensitivity and specificity for detecting initial and cavitated caries lesions by students in third, fourth and fifth year of the Degree in Dentistry at the University of Barcelona, analysing if there is any difference between the diagnoses and treatments among the different years and each student's clinical experience.
View Article and Find Full Text PDFEnvironmental stress differentially affects phenotypic modularity and fluctuating asymmetry in generalist and specialist cactophilic Drosophila.
J Evol Biol
January 2025
Laboratorio de Ecotono, Instituto de Investigaciones em Biodiversidad y Medioambiente (INIBIOMA), CONICET- Universidad Nacional del Comahue, San Carlos de Bariloche, Río Negro, Argentina.
Modularity and developmental (in)stability have the potential to influence phenotype production and, consequently, the evolutionary trajectories of species. Depending on the environmental factors involved and the buffering capacity of an organism, different developmental outcomes are expected. Cactophilic Drosophila species provide an established eco-evolutionary model with well-studied ecological conditions, making them ideal for studying these phenomena.
View Article and Find Full Text PDFInsights into VTE risk in trauma patients: an observational study in an Irish trauma patient population.
Ir J Med Sci
January 2025
School of Pharmacy and Biomolecular Sciences (PBS), Royal College of Surgeons in Ireland, Dublin 2, Ireland.
Background: The rate of VTE in trauma patients varies significantly in the reported literature. We aimed to determine the incidence of VTE in trauma patients in a trauma-receiving hospital over a 7-year period. We sought to evaluate the timing and nature of VTE events and explore the patterns of co-occurrence between PE and DVT, while factoring in clinical care and death outcome.
View Article and Find Full Text PDFOptimization of a micro-scale air-liquid-interface model of human proximal airway epithelium for moderate throughput drug screening for SARS-CoV-2.
Respir Res
January 2025
Department of Pediatrics, David Geffen School of Medicine, UCLA Children's Discovery and Innovation Institute, Mattel Children's Hospital UCLA, UCLA, Los Angeles, CA, 90095, USA.
Background: Many respiratory viruses attack the airway epithelium and cause a wide spectrum of diseases for which we have limited therapies. To date, a few primary human stem cell-based models of the proximal airway have been reported for drug discovery but scaling them up to a higher throughput platform remains a significant challenge. As a result, most of the drug screening assays for respiratory viruses are performed on commercial cell line-based 2D cultures that provide limited translational ability.
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