In the paper a case of mild cognitive impairment is presented. It is interesting because of its atypical psychopathological picture. The primary disorder is accompanied with symptoms of depression and anxiety. A course of diagnosis and treatment are outlined.
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Impact of Frailty on Surgical Outcomes of Patients With Cushing Disease Using the Multicenter Registry of Adenomas of the Pituitary and Related Disorders Registry.
Neurosurgery
February 2025
Global Neurosciences Institute, Philadelphia , Pennsylvania , USA.
Background And Objectives: Despite growing interest in how patient frailty affects outcomes (eg, in neuro-oncology), its role after transsphenoidal surgery for Cushing disease (CD) remains unclear. We evaluated the effect of frailty on CD outcomes using the Registry of Adenomas of the Pituitary and Related Disorders (RAPID) data set from a collaboration of US academic pituitary centers.
Methods: Data on consecutive surgically treated patients with CD (2011-2023) were compiled using the 11-factor modified frailty index.
Scapho-metacarpal dual mobility prosthesis for TMC-1 joint salvage: technical insights.
Arch Orthop Trauma Surg
January 2025
BG Klinikum Unfallkrankenhaus Berlin, Department of Hand-, Replantation- and Microsurgery and Chair of Hand-, Replantation- and Microsurgery, Charité Universitätsmedizin Berlin, Berlin, Germany.
Introduction: Rhizarthrosis, or osteoarthritis of the trapeziometacarpal joint, predominantly affects women over 50, with up to 30% experiencing some degree of arthritis in this joint. Traditional surgical approaches, such as trapeziectomy with ligament reconstruction, can result in some patients in persistent pain or limited functionality. TMC ball-in-socket arthroplasty, with a cup placed in the distal scaphoid, offers a promising alternative to traditional arthrodesis or resection-suspension arthroplasty.
View Article and Find Full Text PDFThird-Generation Trabecular Micro-Bypass Implantation with Phacoemulsification for Glaucoma.
Ophthalmol Ther
January 2025
Rocky Vista University, Englewood, CO, USA.
Introduction: This retrospective, consecutive, real-world case series assessed the efficacy and safety of third-generation trabecular micro-bypass stent implantation (iStent infinite) with phacoemulsification in patients with mild-to-moderate primary open-angle glaucoma (POAG).
Methods: Patients underwent phacoemulsification combined with implantation of iStent infinite (containing three stents) by a single U.S.
The role of the Systemic Inflammatory Response Index (SIRI) and other maternal biochemical markers in determining the severity of intrahepatic cholestasis of pregnancy.
Ginekol Pol
January 2025
Başakşehir Çam and Sakura City Hospital, Department of Perinatology, Istanbul, Türkiye.
Objectives: To investigate the roles of the systemic inflammatory response index (SIRI) and other biochemical markers obtained from maternal blood in determining the diagnosis and severity of pregnancy cholestasis.
Material And Methods: In this retrospective case-control study, a total of 815 pregnant women including 546 healthy pregnant women [serum total bile acid (TBA) level < 10 μmol/L, control group], 185 patients with mild cholestasis [serum TBA level < 40 μmol/L, mild intrahepatic cholestasis of pregnancy (ICP) group] and 84 patients with severe cholestasis (serum TBA level ≥ 40 μmol/L, severe ICP group) were evaluated. The groups were compared regarding demographic data, clinical characteristics, SIRI (neutrophilcount*monocytecount/lymphocyte count), and other laboratory data.
Double-vestibular incision subperiosteal tunnel access (double-VISTA) with connective tissue graft for treating multiple gingival recessions: 2-year follow-up.
Clin Adv Periodontics
January 2025
Department of Orofacial Sciences, School of Dentistry, University of California San Francisco, San Francisco, California, USA.
Background: Gingival recession has a multifactorial etiology, involving various predisposing and precipitating factors. Non-carious cervical lesions (NCCLs) are often associated with gingival recession and pose challenges due to their complex pathodynamics. There is limited evidence regarding tunnel-based procedures combined with connective tissue grafts (CTGs) for treating recession-associated NCCLs.
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