In an open, double-blind study of phencyclidine intoxication, 21 white male subjects were later found to have instead ingested ketamine. These subjects were divided into two cohorts, one treated with 5 mg intramuscular haloperidol and the second with an active placebo. Assessment with the Brief Psychiatric Rating Scale revealed significant reduction in symptoms with haloperidol.
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http://dx.doi.org/10.1097/00045391-200007060-00008 | DOI Listing |
J Clin Med
December 2024
Department of Anaesthesiology and Intensive Care, Hospital Clìnico Universitario de Valencia, University of Valencia, 46003 Valencia, Spain.
: Ketamine offers effective pain relief with fewer side effects than traditional analgesics, making it a promising alternative for acute pain treatment. However, further research is needed to fully assess its role in perioperative care. This umbrella review aimed to compile the highest-quality evidence available regarding the application of ketamine in managing acute pain.
View Article and Find Full Text PDFWorld J Biol Psychiatry
January 2025
P1vital, Wallingford, UK.
Objectives: While neuropsychological effects of conventional antidepressants are well-documented, more research is needed for rapid-acting antidepressants. This study examines the effects of esketamine on emotion processing and cognitive functioning, both acutely and sub-chronically.
Methods: Eighteen treatment-resistant depression (TRD) patients received repeated intravenous esketamine infusions.
A A Pract
January 2025
Division of Anaesthesiology and Perioperative Medicine, Department of Pain Medicine, Singapore General Hospital, Singapore.
Paediatr Anaesth
January 2025
Department of Anaesthesia, Starship Children's Hospital, Auckland, New Zealand.
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