Background: Numerous lasers are currently available for hair removal, yet there are still few studies that have examined the role of fluence, light dose, hair color, and treatment number in laser hair reduction.
Objective: To demonstrate the efficacy and safety of a scanning 800 nm diode laser for hair reduction.
Methods: An 800 nm scanning diode laser was used to deliver 24, 38, or 48 J/cm2 to a 3 cm x 3 cm area of skin located on the back, groin/bikini area, or thigh in 36 adult patients with varying shades of brown or black hair. Patients received one to four treatments during the course of the study. Hair loss was evaluated at both 30 and 90 days after final treatment. Biopsies were obtained from 20 consenting patients.
Results: Significant fluence-dependent hair reduction was demonstrated between treatment and control groups. At 48 J/cm2, the highest dose, a mean hair reduction of 43% was achieved 30 days after the final treatment, and 34% was achieved 90 days after the final treatment. Darker hairs were more effectively treated than lighter hairs.
Conclusions: Hair reduction can be safely and effectively achieved using a scanning 800 nm diode laser.
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http://dx.doi.org/10.1046/j.1524-4725.2001.00297.x | DOI Listing |
J Neurosci
January 2025
Flaum Eye Institute, Department of Ophthalmology, University of Rochester Medical Center, Rochester, New York, 14642, USA;
The inner ear houses both hearing and balance sensory modalities. The hearing and balance organs consist of similar cell types, including sensory hair cells and associated supporting cells. Previously we showed that is required for maintaining supporting cell survival during cochlear maturation.
View Article and Find Full Text PDFLife (Basel)
November 2024
MAC Gifu Research Institute, MicroAlgae Corporation, 4-15 Akebono-cho, Gifu 500-8148, Japan.
This study investigated the multifaceted benefits of water extract across various cell lines, including murine B16F1 melanoma cells, human keratinocyte HaCaT cells, and human follicle dermal papilla cells (HFDPCs), to assess its potential in skin health improvement. Initially, the antioxidant capacity of the extract was evaluated using the ABTS assay, revealing significant radical scavenging activity, indicating strong antioxidative properties. Subsequently, extract showed notable inhibition of α-MSH-enhanced melanin production in B16F1 cells without cell toxicity by suppressing tyrosinase expression.
View Article and Find Full Text PDFMutations in the gene cause the most common form of human hereditary hearing loss, known as DFNB1. is expressed in two cell groups of the cochlea-epithelial cells of the organ of Corti and fibrocytes of the inner sulcus and lateral wall-but not by sensory hair cells or neurons. Attempts to treat mouse models of DFNB1 with AAV vectors mediating nonspecific expression have not substantially restored function, perhaps because inappropriate expression in hair cells and neurons could compromise their electrical activity.
View Article and Find Full Text PDFPregnancy is a period of profound biological transformation. However, we know remarkably little about pregnancy-related brain changes. To address this gap, we chart longitudinal changes in brain structure during pregnancy and explore potential mechanisms driving these changes.
View Article and Find Full Text PDFJ Drugs Dermatol
January 2025
Background: Exosomes are small extracellular vesicles (30-150 nm in size) that play a critical role in cellular communication, transporting proteins, lipids, and nucleic acids between cells. This literature review focuses on evaluating the potential benefits and limitations of exosomes in enhancing skin health and aesthetics through indications such as skin rejuvenation, hair restoration, and pigmentation disorders.
Methods: A thorough literature search was conducted on PubMed using specific MeSH, including "exosomes," "aesthetics," "cosmetic dermatology," "skin rejuvenation," "hair growth," and "wrinkle reduction.
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