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Mucormycosis Causing Splenic Infarction, Gastric Fistula, and Brain Abscess in a Patient With Acute Myeloid Leukemia: A Case Report.
Case Rep Infect Dis
December 2024
Hospital Infection Control Department, Hospital de Base, Federal District, Brasilia, Brazil.
Invasive mucormycosis is an aggressive fungal infection characterized by rapid progression, primarily impacting immunocompromised individuals. Herein, we report a case of splenic infarction in association with gastrointestinal fistula and brain abscess as a rare presentation of mucormycosis biopsy, proven in a 56-year-old patient diagnosed with acute myeloid leukemia. The patient initially sought medical attention with a 3-week history of fever, night sweats, and malaise.
View Article and Find Full Text PDFCD23 expression in lymphoplasmacytic lymphoma: Clinical-pathological and biological correlations.
Histopathology
December 2024
Pathology Unit, Department of Medicine-DIMED, University of Padua School of Medicine, Padua, Italy.
Aims: The diagnosis of lymphoplasmacytic lymphoma (LPL) in the bone marrow (BM) is challenged by aberrant phenotypes and by overlapping histological features with marginal zone lymphoma (MZL). To address these issues, we (i) assessed LPL immunophenotype on a large series of BM samples, (ii) drew possible correlations between LPL phenotype and clinical/molecular data and (iii) investigated the role of new phenotypical markers in the differential diagnosis between LPL and MZL.
Materials And Methods: The study retrospectively considered 81 clinically annotated LPL diagnosed at Padua University Hospital (Padua, Italy) during a 5-year period.
Graft inflow modulation in recipients with portal hypertension.
Updates Surg
December 2024
Department of Clinical Medicine and Surgery, Division of Minimally Invasive and Robotic HPB Surgery, Transplantation Service, Federico II University Hospital, Via Sergio Pansini 5, 80131, Naples, Italy.
The extended application of living donor liver transplantation (LDLT) has revealed the problem of graft size mismatching, potentially leading to the "small-for-size syndrome" (SFSS). SFSS is a rare dysfunction that may affect a partial liver graft, characterized by coagulopathy, cholestasis, ascites, and encephalopathy. A key role in the physiopathology of SFSS is played by portal hypertension (PHT) to which a small allograft is submitted after reperfusion, resulting in sinusoidal congestion and hemorrhage.
View Article and Find Full Text PDFGrowth performance and immune response of broilers during active infection are modified by dietary inclusion of canola meal or corn-DDGS in reduced-protein corn-soybean meal diets.
Anim Nutr
December 2024
Department of Poultry Science, University of Georgia, Athens, GA, USA.
Article Synopsis
- - The study aimed to investigate the effects of replacing soybean meal (SBM) with canola meal (CM) or corn-distillers' dried grains with solubles (cDDGS) in reduced-protein diets on infected broiler chicks, using a sample of 1,120 birds divided into various diet and infection groups.
- - Results indicated that while the diet had little effect on uninfected birds, the RP-SBM diet led to higher weight gain in infected birds and significant immune responses, such as increased bile anti-IgA and splenocyte proliferation.
- - The findings suggest that partial replacement of SBM with CM or cDDGS offers minimal benefits, with only the RP-SBM diet showing notable positive outcomes
Parkin-TLR4-NLRP3 Axis Directs Melatonin to Alleviate Atrazine-Induced Immune Impairment in Splenic Macrophages.
J Pineal Res
November 2024
College of Veterinary Medicine, Northeast Agricultural University, Harbin, China.
Atrazine (ATR) is a widespread environmental herbicide that seriously affects agricultural work and human safety. Melatonin (MLT) as an endogenous neuroendocrine hormone is widely found in animals and plants, which have antioxidant and anti-inflammatory effects. Pink1/Parkin-mediated mitophagy keeps normal physiological processes by degrading damaged mitochondria in cells.
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