Morphological changes in inguinal lymph nodes, lymphatic collector and subcutaneous space were studied up in patients with the lower extremities lymphoedema. While the lower extremities lymphoedema occurs in inguinal lymph nodes the connective tissues spreading in two variants is observed. In the first one fibroblasts and collagen fibres appears in medullar substance (chordae medullaris and medullar sinuses) and in the second the sclerosis process begins from cortical plateau and paracortical zone. It is expedient to include the intraarterial infusion of the xenospleen preparations in complex of treatment of patients with initial stage of the lower extremities lymphoedema, especially in the absence of possibility to proceed with microsurgical intervention and the erysipelas presence in anamnesis.

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