AI Article Synopsis
- - The study found that weaver mice have more tyrosine hydroxylase-immunoreactive fibers in their retinal nerve fiber layer compared to normal mice.
- - A new technique for examining the optic nerve confirmed that these fibers appear first in the optic nerve at post-natal day 12, and then in the retina at post-natal day 13.
- - An observation was made of a looping fiber in the retina of a monkey fetus, indicating a similar process may occur in other species.
Article Abstract
The number of tyrosine hydroxylase-immunoreactive fibers in the nerve fiber layer is increased in the retina of the weaver compared to control mice (Dev. Brain Res. 121 (2000) 113). To confirm the retinopetal/centrifugal nature of these fibers, a newly devised whole-mounted optic nerve technique allowed us to determine, during development, their first appearance within the optic nerve (post-natal day 12) compared to retina (post-natal day 13). One such fiber was also observed looping in the retina of a monkey fetus.
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| http://dx.doi.org/10.1016/s0165-3806(01)00103-1 | DOI Listing |
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