The Wisconsin card sorting test and the Weigl test are two neuropsychological tools widely used in clinical practice to assess frontal lobe functions. In this study we present norms useful for Italian subjects aged from 15 to 85 years, with 5-17 years of education. Concerning the Wisconsin card sorting test, a new measure of global efficiency (global score) is proposed as well as norms for some well known qualitative aspects of the performance, i.e. perseverative responses, failure to maintain the set and non-perseverative errors. In setting normative values, we followed a statistical methodology (equivalent scores) employed in Italy for other neuropsychological tests, in order to favour the possibility of comparison among these tests. A correlation study between the global score of the Wisconsin card sorting test and the score on the Weigl test was carried out and it emerges that some cognitive aspects are not overlapping in these two measures.
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Waste Manag
January 2025
Chair of Waste Processing Technology and Waste Management, Montanuniversitaet Leoben, Leoben, Austria. Electronic address:
Global waste generation is projected to reach 3.40 billion tons by 2050, necessitating improved waste sorting for effective recycling and progress toward a circular economy. Achieving this transformation requires higher sorting intensity through intensified processes, increased efficiency, and enhanced yield.
View Article and Find Full Text PDFPharmaceuticals (Basel)
January 2025
Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Beni-Suef University, Beni-Suef 62514, Egypt.
: Mirtazapine (MRZ) is a psychotropic drug prescribed to manage serious sorts of depression. By virtue of its extensive initial-pass metabolic process with poor water solubility, the ultimate bioavailability when taken orally is a mere 50%, necessitating repeated administration. The current inquiry intended to fabricate nose-to-brain chitosan-grafted cationic leciplexes of MRZ (CS-MRZ-LPX) to improve its pharmacokinetic weaknesses and boost the pharmacodynamics aspects.
View Article and Find Full Text PDFMaterials (Basel)
January 2025
School of Aeronautic Science and Engineering, Beihang University, Beijing 100191, China.
The structure of thermoset composite laminated plates is made by stacking layers of plies with different fiber orientations. Similarly, the stiffened panel structure is assembled from components with varying ply configurations, resulting in thermal residual stresses and processing-induced deformations (PIDs) during manufacturing. To mitigate the residual stresses caused by the geometric features of corner structures and the mismatch between the stiffener-skin ply orientations, which lead to PIDs in composite-stiffened panels, this study proposes a multi-objective stacking optimization strategy based on an improved adaptive genetic algorithm (IAGA).
View Article and Find Full Text PDFMicromachines (Basel)
January 2025
School of Mechanical and Automotive Engineering, South China University of Technology, Guangzhou 510640, China.
In microfluidic chips, glass free-form microchannels have obvious advantages in thermochemical stability and biocompatibility compared to polymer-based channels, but they face challenges in processing morphology and quality. Hence, picosecond laser etching with galvanometer scanning is proposed to machine spiral microfluidic channels on a glass substrate. The objective is to disperse and sort microparticles from a glass microchip that is difficult to cut.
View Article and Find Full Text PDFBrain Sci
December 2024
Department of Health and Human Physiology, University of Iowa, Iowa City, IA 52242, USA.
Background/objectives: Cognitive functions are a crucial part of daily living, especially for adults with Down syndrome (DS) who have a high likelihood of developing Alzheimer's disease in adulthood. In addition, adults with DS move slower and are not meeting the standard aerobic activity guidelines each week. The aim of this study was to examine if Assisted Cycle Therapy (ACT) would improve cognitive planning as measured by the Tower of London (TOL), set switching as measured by the modified Wisconsin Card Sorting Test, and spatial memory as measured by the Corsi Block Test in adults with DS as compared to self-paced cycling.
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