An event-related potential study of older children with an early history of failure to thrive.

Dev Neuropsychol

Department of Pediatrics, University of Arkansas for Medical Sciences, Center for Applied Research & Evaluation, Arkansas Children's Nutrition Center, Arkansas Children's Hospital, USA.

Published: July 2001

Elementary and junior high school children (n = 13), who were diagnosed with nonorganic failure to thrive (FTT) as infants and toddlers, were compared with a normal control group (n = 14) on visual event-related potentials (ERPs) elicited during a primed lexical decision task. Positive stimuli were real words that were identical to the priming stimuli; negative stimuli were nonpronounceable letter strings. Although the groups did not differ in word-list reading level, the former FTT group had slower reaction (decision) times and did not show ERP evidence of priming in the N400 epoch. Anterior sites yielded better separation of the real words and letter strings than posterior sites. A late anterior component between 500 msec to 650 msec poststimulus onset showed the largest condition effect for both groups. The control group had a larger negative going late anterior component to words than the FTT group. The combined reaction time and ERP findings point to less automatized word recognition in the FTT group.

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http://dx.doi.org/10.1207/S15326942DN1802_3DOI Listing

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