The structures of the butenolides 1 and 2, isolated from the endemic plants Hortonia floribunda, H. angustifolia, and H. ovalifolia, collected in Sri Lanka, have been elucidated by spectroscopic analysis. These compounds exhibited potent mosquito larvicidal activity against the second instar larvae of Aedes aegypti.
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Molecules
January 2025
College of Chemistry and Chemical Engineering, Taiyuan University of Technology, Taiyuan 030024, China.
A series of novel triazone derivatives containing aldehyde hydrazone or ketone hydrazone moieties were designed, synthesized and their biological activities were investigated against , , , , and 14 Kinds of fungi. Most of the aldehyde hydrazone exhibited excellent insecticidal activities against . In particular, the aphicidal activities of compounds (35%) and (30%) were equivalent to pymetrozine (30%) at 5 mg/kg.
View Article and Find Full Text PDFToxics
January 2025
Department of Biotechnology, Institute of Biotechnology, School of Life and Applied Sciences, Yeungnam University, Gyeongsan 38541, Republic of Korea.
Recently, there has been a growing demand for plant-based products to treat a range of health conditions. (L.), a member of the Lamiaceae family, is widely known for its versatile therapeutic properties.
View Article and Find Full Text PDFBull Math Biol
January 2025
Department of Biology, Memorial University of Newfoundland, St. John's, NL, Canada.
Mosquitoes are important vectors for the transmission of some major infectious diseases of humans, i.e., malaria, dengue, West Nile Virus and Zika virus.
View Article and Find Full Text PDFPest Manag Sci
January 2025
Department of BioMolecular Sciences and the Research Institute of Pharmaceutical Sciences, School of Pharmacy, University of Mississippi, University, USA.
Background: 1,4-Naphthoquinone compounds have shown pesticidal activity against Aedes aegypti larvae, a key vector of diseases such as dengue and Zika. However, limited knowledge of their structure-activity relationships has hindered their optimization for pesticide development. This study investigates the structure-activity relationships of 1,4-naphthoquinone, particularly 2-hydroxy-1,4-naphthoquinone and its derivatives.
View Article and Find Full Text PDFWellcome Open Res
December 2024
Department of Vector Biology, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, L3 5QA, UK.
Background: , a malaria mosquito originally from South Asia and the Middle East, has been expanding across both Asia and Africa in recent decades. The invasion of this species into sub-Saharan Africa is of particular concern given its potential to increase malaria burden, especially in urban environments where thrives. Whilst surveillance of this vector in Africa has recently increased markedly there is a need to review the existing methods of control so that we can stop, rather than simply monitor, its spread in Africa.
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