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Article Synopsis
  • Oral focus screening before hematopoietic cell transplantation (HCT) is critical, yet the impact of chronic dental issues on post-transplant health is not well understood.
  • A study of 500 patients highlighted that nearly half had untreated chronic dental problems, and those with three or more issues stayed in the hospital five days longer on average.
  • The research found that while having multiple dental foci increased hospital length of stay, it did not significantly affect early mortality rates post-HCT.
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As periodontal and endodontic tissues have a close association, they come into close touch and have a lot of possible places for communication. In a clinical setting, this correlation promotes infection spread and results in the typical endo-perio lesion appearance. Because the two tissues are in close touch with one another, managing such lesions can be difficult.

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Objective: The aim of this article is to analyze the latest scientific literature and focus on the development of second-generation platelet concentrates: platelet-rich fibrin (PRF) and concentrated growth factor (CGF), their fabrication procedure and capability in periodontal surgery.

Material And Methods: Scientific articles published in English were selected from PubMed and Cochrane Library databases according to selected keywords. Duplicate and off-topic articles were excluded from further analysis.

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In the last decades, Periodontal Regeneration has been one of the most discussed topics in Periodontics, attracting the attention of researchers and clinicians. This can be justified by the evident and continuous progress observed in the field, characterized by a better understanding of the biological mechanisms involved, significant improvement of operative and technical principles, and the emergence of a wide range of biomaterials available for this purpose. Together, these aspects put the theme much in evidence in the search for functional and esthetic therapeutic solutions for periodontal tissue destruction.

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When modeling a detoxifying organ function, an important component is the impact of flow on the metabolism of a compound of interest carried by the blood. We here study the effects of red blood cells (such as the Fahraeus-Lindqvist effect and plasma skimming) on blood flow in typical microcirculatory components such as tubes, bifurcations and entire networks, with particular emphasis on the liver as important representative of detoxifying organs. In one of the plasma skimming models, under certain conditions, oscillations between states are found and analyzed in a methodical study to identify their causes and influencing parameters.

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