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Effect of Dietary Supplementation of Red and Larch Pine Needle Powders on Productivity, Egg Quality, Yolk Fatty Acids and Cholesterol and Hatchability of Laying Quails.
J Anim Physiol Anim Nutr (Berl)
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Faculty of Agriculture Department of Animal Science, Sehit Bülent Yurtseven Kampüsü, Igdır University, Igdir, Turkey.
This study aimed to determine the efficacy of red pine and larch pine needles powder at different doses on productive performance, egg quality, hatching parameters, total fatty acid and cholesterol levels of laying quails. A total of 126 (84 ♀ and 42 ♂) 20-week-old laying quail were randomly distributed into seven experimental diets with three replicates of six (four female and two male) birds per cage. The groups were fed a basal diet (CON group), a basal diet with red pine needle powder (RPNP group) (1.
View Article and Find Full Text PDFNovel Dehydroabietylamine C-Ring Schiff Base Derivatives: Synthesis, Antiproliferative activity, DNA binding and Molecular docking.
Chem Asian J
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Nanjing Forestry University, College of Science, CHINA.
A series of Dehydroabietylamine (DHAA) C-ring Schiff derivatives, L3-L20, were synthesized and their in vitro cytotoxic activity against the human tumor cell lines cervix HeLa, breast MCF-7, lung A549, liver HepG2, and the nonmalignant cell line umbilical vein HUVEC was investigated. Most of the compounds showed varying degrees of anticancer activity against HeLa cell lines while demonstrating lower toxicity to normal HUVEC cells compared to DHAA and doxorubicin (DOX), especially compound L19, which not only enhanced the anticancer activity of DHAA, but also significantly reduced the toxicity to normal cells, achieving a selectivity index (SI) 118 times higher than that of DHAA and 245 times higher than that of DOX. In addition, compound L19 induced apoptosis in HeLa cells in a dose-dependent manner and arrested the cell cycle in S phase.
View Article and Find Full Text PDFPatient centered medication treatment for opioid use disorder in rural Vermont: a qualitative study.
Addict Sci Clin Pract
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Center for Technology and Behavioral Health, Geisel School of Medicine, Dartmouth College, Lebanon, NH, 03766, USA.
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View Article and Find Full Text PDFCharacterization and interactions between piperine and ezetimibe in their Anti-hyperlipidemic efficacy using Biopharmaceutics and Pharmacokinetics.
BMC Pharmacol Toxicol
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Department of Pharmaceutics and Pharmaceutical Technology, Kampala International University, Western Campus, P.O. Box 71, Ishaka - Bushenyi, Uganda.
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View Article and Find Full Text PDFRegulatory roles of eugenol in paraquat-altered SNCA/LZTS3/MAPT in the cerebellum of Wistar rats.
Lab Anim Res
January 2025
Anatomy Department, Faculty of Basic Medical Sciences, Alex Ekwueme, Federal University, Ndufu-Alike, Ebonyi State, Nigeria.
Background: The Microtubules-associated protein tau (MAPT), alpha-synuclein (SNCA), and leucine zipper tumor suppressor 3 (LZTS3) genes are implicated in neurodegeneration and tumor suppression, respectively. This study investigated the regulatory roles of eugenol on paraquat-altered genes.
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