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Inputs of pharmacoepidemiology in addictovigilance: How do they fit together?
Therapie
October 2024
Inserm, Aix-Marseille université, U1106, 13005 Marseille, France; Service de pharmacologie clinique et pharmacosurveillance, unité de pharmacoépidémiologie, Assistance publique-Hôpitaux de Marseille, 13009 Marseille, France; Service de pharmacologie clinique et pharmacosurveillance, centre d'évaluation et d'information sur la pharmacodépendance - addictovigilance, Assistance publique-Hôpitaux de Marseille, 13009 Marseille France.
The French Addictovigilance Network has been using data from the French Heath insurance since the late 1990s to assess prescription drug abuse. In this narrative review, we illustrate the inputs of pharmacoepidemiology in addictovigilance based on the experience of the French Addictovigilance Network. The review focuses on pharmacoepidemiology using the French National Health Data System.
View Article and Find Full Text PDFMegadose Vitamin C Prescription Through Alternative Medicine Leading to End-Stage Renal Disease: Case Study and Literature Review.
J Investig Med High Impact Case Rep
March 2023
Kaweah Delta Medical Center, Visalia, CA, USA.
Modern medicine has made tremendous advancements and succeeded in increasing longevity through adequate screening and diagnosis and various new therapeutic approaches. However, alternative medicine is a branch of health care practicing different traditional and unconventional, potentially hazardous therapies to treat commonly known ailments. Standard low-dose vitamin C, ie, 500-1000 mg, is approved in medical conditions like methemoglobinemia, scurvy, burns and also helps iron absorption in anemia.
View Article and Find Full Text PDFAllogeneic hematopoietic stem cell transplantation to cure sickle cell disease: A review.
Front Med (Lausanne)
February 2023
Centre for Stem Cell Research, Christian Medical College, Vellore, Tamilnadu, India.
Sickle cell disease (SCD) had first been mentioned in the literature a century ago. Advancement in the molecular basis of the pathophysiology of the disease opens the door for various therapeutic options. Though life-extending treatments are available for treating patients with SCD, allogeneic hematopoietic stem cell transplantation (HSCT) is the only option as of yet.
View Article and Find Full Text PDFHLA-haploidentical hematopoietic stem cells transplantation with regulatory and conventional T-cell adoptive immunotherapy in pediatric patients with very high-risk acute leukemia.
Bone Marrow Transplant
May 2023
Pediatric Oncology-Hematology Unit, Santa Maria della Misericordia Hospital, Perugia, Italy.
Allogeneic hematopoietic stem cell transplantation (HSCT) is still needed for many children with very high-risk acute leukemia. An HLA-haploidentical family donor is a suitable option for those without an HLA-matched donor. Here we present outcomes of a novel HLA-haploidentical HSCT (haplo-HSCT) strategy with adoptive immunotherapy with thymic-derived CD4CD25 FoxP3 regulatory T cells (Tregs) and conventional T cells (Tcons) performed between January 2017 and July 2021 in 20 children with high-risk leukemia.
View Article and Find Full Text PDFDietary Vitamin A Intake, Coverage of Vitamin A Megadose Supplementation, and Prevalence of Vitamin A Deficiency among Marginalized Children 6-59 Months in Anganwadis of Chandigarh: A Multistage Cluster Sampling Survey.
Indian J Community Med
December 2021
Department of Pediatrics, Advanced Pediatrics Center, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Background: Lack of recent local data regarding Vitamin A deficiency, dietary intake, and coverage of biannual high-dose Vitamin A prophylaxis among marginalized children poses challenges for policy change.
Objective: Our study aimed to evaluate the burden of serum Vitamin A deficiency, dietary Vitamin A intake, and current Vitamin A supplementation coverage.
Methodology: We enrolled 216 children aged 6-60 months from 30 Anganwadis of Chandigarh using two-stage cluster sampling.
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