The segregation pattern of an attached X chromosome with several Y-autosome translocations conflicts with the expectations based on the distributive pairing hypothesis because the chromosomes segregating from the translocation configuration include both exchange and non-exchange chromosomes. The results of the second experiment involving three compound chromosomes go even further; they suggest that the essential association which determines the segregation of nonhomologous elements is in fact set up prior to the time of crossing over.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1213259 | PMC |
http://dx.doi.org/10.1093/genetics/79.1.63 | DOI Listing |
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