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[All-trans retinoic acid combined with low-dose cytosine arabinoside treatment for acute myelogenous leukemia with trilineage myelodysplasia--a case report]. | LitMetric
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[All-trans retinoic acid combined with low-dose cytosine arabinoside treatment for acute myelogenous leukemia with trilineage myelodysplasia--a case report].

N Maeda S Satake Y Okada S Asahara N Hasuike M Tamura M Takata K Tasaka T Okutani Y Maeda Y Tomofuji T Chinzei K Saigo

Gan To Kagaku Ryoho

Dept. of Internal Medicine, Kakogawa Municipal Hospital.

Published: March 2001

AML with trilineage myelodysplasia (AML/TMDS) is recognized as having of poor prognosis due to its resistance to chemotherapy in comparison with de novo AML. An AML/TMDS patient who failed to respond to ordinary induction therapy achieved complete remission with combination therapy consisting of all-trans retinoic acid (ATRA) and low-dose Ara-C. No serious toxicity was observed. ATRA combined with low-dose Ara-C could be an alternative treatment for this kind of patient.

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