Natural and synthetic biostimulants have been studied for their effect on resistance of soil microbe associations to pesticides. It has been shown that in the presence of growth-stimulating preparations (ivin, emistym, agrostimulin) in the microbial groups the number of microorganisms resistant to such fungicides as phenpiclonyl, fluodioxonyl, diphenoconasol increases. The activity of redox-systems which can initiate the oxidative destruction of pesticides increased in microbial associations under the simultaneous use of biostimulants and fungicides.

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