AI Article Synopsis
- A study investigated the impact of vaccinating HIV-1 patients with undetectable viral loads (VL) achieved through effective antiretroviral therapy during the 1998 flu season.
- Thirty-nine HIV-1-infected patients with VL<20 copies/ml for at least six months were vaccinated, with a control group for comparison.
- Results showed no significant difference in the proportion of patients with undetectable VL between vaccination and control groups after two and four weeks, suggesting the flu vaccine does not affect viral load in these patients.
Article Abstract
The effect of vaccinating patients with sustained undetectable HIV-1 viremia (VL) achieved with highly active antiretroviral therapy was prospectively investigated. During the 1998 influenza immunization period, 39 HIV-1-infected patients who showed a VL<20 copies/ml for at least 6 months before the study entry date were vaccinated for influenza. Twenty-two vaccinees were immunized at entry. Seventeen controls were followed for 4 weeks after entry, crossing over then to the vaccination group. The proportion of patients with undetectable VL was not significantly different between the vaccination and control groups 2 and 4 weeks after entry. Therefore, influenza immunization of patients with undetectable viremia achieved with highly active antiretroviral therapy does not seem to affect VL.
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| http://dx.doi.org/10.1007/s100960000421 | DOI Listing |
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