Aim: To study epidemiology of acute coronary conditions (ACC) including acute myocardial infarction (AMI) and acute coronary failure (ACF) among female population of Tomsk aged over 20 years and trends for 5 years.

Material And Methods: 1919 ACC episodes were compared in the women: 1616(84.2%) cases of AMI and 303(15.8%) cases of ACF. The comparison concerned epidemiological indices: morbidity, hospital and prehospital ACC lethality, the disease history, pathomorphological evidence.

Results: ACC prevalence among women for 5 years remained at the level 2.0-2.2 cases per 1000 women of the same age. Number of ACC patients with progressive angina decreased while number of cases of cardiogenic shock went up in paralled decrease of the number of episodes of acute left ventricular failure, arrhythmia and abnormal conduction. AMI as macrofocal occurred more frequently, ACC hospital lethality rose (due to more cases in patients over 60). Autopsy showed more cases of stenosing atherosclerosis of coronary arteries.

Conclusion: No changes for the better occurred for 5 years among female population of Tomsk in relation to ACC incidence and mortality. This necessitates introduction of measures of effective primary and secondary prevention of ischemic heart disease and arterial hypertension.

Download full-text PDF

Source

Publication Analysis

Top Keywords

acute coronary
8
female population
8
population tomsk
8
acc
7
cases
6
[acute coronary
4
coronary events
4
events female
4
female residents
4
residents tomsk
4

Similar Publications

The acute response to therapeutic afterload reduction differs between heart failure with preserved (HFpEF) versus reduced ejection fraction (HFrEF), with larger left ventricular (LV) stroke work augmentation in HFrEF compared to HFpEF. This may (partially) explain the neutral effect of HFrEF-medication in HFpEF. It is unclear whether such differences in hemodynamic response persist and/or differentially trigger reverse remodeling in case of long-term afterload reduction.

View Article and Find Full Text PDF

Catheter-directed therapy for pulmonary embolism in pediatrics: a systematic review and meta-analysis.

Thromb J

January 2025

Pediatric Emergency Department, St. Christopher's Hopsoital for Children, Philadelphia, PA, USA.

Background: Acute pulmonary embolism (PE) is a serious and potentially fatal condition that is relatively rare in the pediatric population. In patients presenting with massive/submassive PE, catheter-directed Therapy (CDT) presents an emerging therapeutic modality by which PE can be managed.

Methods: Electronic databases were systematically searched through May 2024.

View Article and Find Full Text PDF

Purpose: Cardiomyocyte death is a major cytopathologic response in acute myocardial infarction (AMI) and involves complex inflammatory interactions. Although existing reports indicating that mixed lineage kinase domain-like protein (MLKL) is involved in macrophage necroptosis and inflammasome activation, the downstream mechanism of MLKL in necroptosis remain poorly characterized in AMI.

Methods: MLKL knockout mice (MLKL), RIPK3 knockout mice (RIPK3), and macrophage-specific MLKL conditional knockout mice (MLKL) were established.

View Article and Find Full Text PDF

Screening for transcriptomic associations with Swine Inflammation and Necrosis Syndrome.

BMC Vet Res

January 2025

Department of Veterinary Clinical Sciences, Clinic for Swine, Justus-Liebig-University, Frankfurter Strasse 112, D-35392, Giessen, Germany.

Background: The recently identified swine inflammation and necrosis syndrome (SINS) affects tail, ears, teats, coronary bands, claws and heels of affected individuals. The primarily endogenous syndrome is based on vasculitis, thrombosis, and intimal proliferation, involving defence cells, interleukins, chemokines, and acute phase proteins and accompanied by alterations in clinical chemistry, metabolome, and liver transcriptome. The complexity of metabolic alterations and the influence of the boar led to hypothesize a polygenic architecture of SINS.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!