Anabolic steroids are synthetic analogues of the natural androgenic 'male' hormone called testosterone that is produced primarily in the testes in males and in the ovaries in females. Anabolic steroids and other agents are fast becoming part of the standard of care for HIV disease, gaining acceptance in reversing loss of lean body mass, increasing muscle strength, improving sexual functioning and appetite and creating a general sense of well-being. This article will review commonly prescribed anabolic agents, discuss potential side effects and contraindications.
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http://dx.doi.org/10.1258/0956462011916893 | DOI Listing |
Clin Endocrinol (Oxf)
January 2025
Department of Cardiology & 65+ Clinic, Sismanogleio-Amalia Fleming General Hospital, Melissia, Greece.
Objective: Ghrelin is emerging as a promising therapeutic option for heart failure (HF) due to its potent inotropic, anabolic, and cardioprotective properties. This review aims to critically examine the available clinical evidence on ghrelin therapy in HF, while also incorporating key findings from preclinical studies that support its therapeutic potential.
Methods: A comprehensive search was conducted in PubMed and the Cochrane Library up to September 15, 2024, using the keywords "heart failure" and "ghrelin.
Zhonghua Yi Xue Za Zhi
January 2025
Department of Orthopedics, General Hospital of the People's Liberation Army, Beijing100853, China.
Osteoporotic fracture is a special type of pathological fracture characterized by high morbidity, high disability, high mortality and low diagnosis and treatment rate. Currently, the main problem with clinical intervention for osteoporotic fractures is the lack of proper understanding by doctors (especially orthopedic surgeons) of the pathologic changes in the disease itself. Aggressive surgical treatment is very important, but it cannot fundamentally solve the serious consequences of delayed healing of osteoporotic fractures and the occurrence of re-fractures.
View Article and Find Full Text PDFPhys Sportsmed
January 2025
Faculty of Sport and Physical Education, University of Novi Sad, Novi Sad, Serbia.
Purpose: This systematic review aims to synthesize the current research on doping in combat sports, examining the prevalence, detection methods, prevention strategies, and overall impact on combat sports.
Design/methodology/approach: Of the 21 identified articles, six met the inclusion criteria. A systematic approach was used, including content analysis based on specific criteria: articles in English, original research, and relevance to sport and doping.
Drug Test Anal
December 2024
Center for Preventive Doping Research, Institute of Biochemistry, German Sport University Cologne, Cologne, Germany.
The 17th edition of the annual banned-substance review on analytical approaches in human sports drug testing is dedicated to literature published between October 2023 and September 2024. As in previous years, focus is put particularly on new or enhanced analytical options in human doping controls as well as investigations into the metabolism and elimination of compounds of interest, which represent central (while not exclusive) cornerstones of the global anti-doping mission. New information published within the past 12 months on established doping agents as well as new potentially relevant substances are reviewed and discussed in the context of the World Anti-Doping Agency's 2024 Prohibited List.
View Article and Find Full Text PDFFront Pharmacol
December 2024
Second Affiliated Hospital of Heilongjiang, University Of Chinese Medicine, Harbin, China.
Osteoporosis (OP) stands as the most prevalent systemic skeletal condition associated with aging. The current clinical management of OP predominantly depends on anti-resorptive and anabolic agents. Nevertheless, prolonged use of some of these medications has been observed to reduce efficacy and elevate adverse effects.
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