In electron beam dosimetry with an ionization chamber, a factor that corrects for the cavity perturbation of the medium, Prepl, and one to account for the disturbance due to the chamber wall material differing from the medium, Pwall, are required. The overall perturbation correction factor, p(q) = PreplPwall, has been introduced because of the difficulty in separately measuring these two components. An advantage of parallel-plate ionization chambers is that p(q) has been shown to be close to unity at dmax. However, many dosimetry applications require knowledge of the overall perturbation factor at depths greater than dmax. We determined p(q) for the NACP chamber at depths beyond dmax by intercomparing percentage depth dose measurements made with it with those obtained with a PTW/diamond detector for which p(q) was taken as unity at all the measurement depths. Data were obtained at depths corresponding to approximately the 90 and 80 per cent of the dose maxima for 20, 16, 12 and 6 MeV incident electrons. The beam energy at depth, Ed, and the percentage depth-dose gradient varied from 1.4 to 14.3 MeV and 0 to 5.8% mm(-1) respectively. Our results show that within the estimated uncertainty of 1.3%, p(q),NACP is unity over the range of energies and dose gradients studied.
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http://dx.doi.org/10.1088/0031-9155/46/2/404 | DOI Listing |
J Exp Clin Cancer Res
January 2025
Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy.
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Chemical and Biological Integrative Research Center, Biomedical Research Division, Korea Institute of Science and Technology, Seoul, Republic of Korea.
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School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
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View Article and Find Full Text PDFAdv Exp Med Biol
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Cancer Biology and Stem Cells Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Wurundjeri Country, Melbourne, Australia.
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