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Molecular Dissection of Phagocytosis by Proteomic Analysis in .
Genes (Basel)
January 2023
Department of Biomedical Chemistry, Graduate School of Medicine, The University of Tokyo, Tokyo 113-0033, Japan.
is the enteric protozoan parasite responsible for amebiasis. Trophozoites of ingest human cells in the intestine and other organs, which is the hallmark of its pathogenesis. Phagocytosis and trogocytosis are pivotal biological functions for its virulence and also contribute to the proliferation of nutrient uptake from the environment.
View Article and Find Full Text PDFHow to get away with murder: The multiple strategies employed by pathogenic protozoa to avoid complement killing.
Mol Immunol
September 2022
Departamento de Parasitologia, Instituto de Ciências Biológicas (ICB), Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil. Electronic address:
Parasitic protozoa are eukaryotic unicellular organisms that depend on a variety of living organisms and can develop intra- and extracellularly inside their hosts. In humans, these parasites cause diseases with a significant impact on public health, such as malaria, toxoplasmosis, Chagas disease, leishmaniasis and amebiasis. The ability of a parasite in establishing a successful infection depends on a series of intricate evolutionarily selected adaptations, which include the development of molecular and cellular strategies to evade the host immune system effector mechanisms.
View Article and Find Full Text PDFRevisiting Drug Development Against the Neglected Tropical Disease, Amebiasis.
Front Cell Infect Microbiol
June 2021
Multidisciplinary Centre for Advanced Research and Studies, Jamia Millia Islamia, New Delhi, India.
Amebiasis is a neglected tropical disease which is caused by the protozoan parasite . This disease is one of the leading causes of diarrhea globally, affecting largely impoverished residents in developing countries. Amebiasis also remains one of the top causes of gastrointestinal diseases in returning international travellers.
View Article and Find Full Text PDFAmebiasis cutis revisited.
J Cutan Pathol
August 2007
Department of Pathology, Nelson R Mandela School of Medicine, University of KwaZulu Natal and Inkosi Albert Luthuli Central Hospital, Congella 4013, Durban, KwaZulu Natal, South Africa.
Background: Amebiasis cutis (AC) is reported infrequently. This study assesses the clinicopathological spectrum, co-existent visceral involvement and impact of human immunodeficiency virus (HIV) co-infection on AC.
Methods: An 8-year prospective clinicopathological evaluation of patients with AC.
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