Background: The in vivo visco-elastic characteristics of skin depend on a series of physiopathological parameters. Among them, the age-related intrinsic tensile properties and the preconditioning of the tissues set under tension by the hypodermal volume might be of importance.
Aims: To revisit the influence of age and body mass on the firmness and mechanical anisotropy of the skin as determined by the velocity of the shear wave propagation.
Method: Resonance running time measurements (RRTM) were performed on the mid volar forearm in 110 adults of both sexes. In each subject 16 RRTM were collected at four different precise angles with regard to the limb axis. We recorded the lowest, the highest and the mean multidirectional RRTM as well as the coefficient of variation (CV) of the latter value. In addition, the body mass index (BMI) was calculated.
Results: Age and BMI did not influence the minimum RRTM. In contrast, the maximum RRTM as well as the mean and CV of the multidirectional RRTM, significantly rose in a progressively increasing proportion of the subjects older than 60 years. These changes were only encountered in subjects with a normal BMI ranging from 18 to 25. Sex-related differences were not disclosed.
Conclusions: The intrinsic skin tension lines identified by the minimum RRTM are not significantly altered with age and BMI variations. In contrast, skin laxity identified by larger maximum and mean multidirectional RRTM may increase after 60 years of age in subjects with a normal BMI. This is accompanied by increased skin mechanical anisotropy identified by CV values of the multidirectional RRTM over 40%.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/s0531-5565(00)00219-9 | DOI Listing |
Dermatology
December 2004
Department of Dermatopathology, University Hospital Sart Tilman, Liège, Belgium.
Background: Diverse skin alterations may develop in patients under chronic haemodialysis. Among them, signs of premature photo-ageing have been described.
Aim: To assess alterations in the physical properties of skin consistent with ageing effects and with cutaneous fluid exchanges during haemodialysis sessions.
Exp Gerontol
February 2001
Department of Dermatopathology, University Medical Center Sart Tilman, B-4000, Liège, Belgium.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!