Objective: The aim of this study was to assess whether or not there was an association between a polycystic ovary (PCO) and fibrocystic breast disease based on ultrasound findings, both pelvic and mammographic.
Design: Prospective case-control study.
Population: Women aged between 18 and 30 years not using oral contraceptives attending the outpatient ultrasound clinic from January 1996 to December 1998.
Main Outcome: Confirm the association between PCO and fibrocystic breast disease.
Results: According to the ultrasound findings, women were allocated to three groups: 351 out of 456 showed normal-appearing ovaries (group A), 93 had polycystic-appearing ovaries/PCO (group B) and 12 had PCO syndrome (group C). In group A, 24 (6.83%) women showed breast pathology. In group B, there was an association between PCO and breast pathology in 53 (56.98%) women, while in group C it was noted in 11 out of 12 (91%).
Conclusion: This study showed a significant association between PCO and benign pathology. This should encourage the performance of a screening breast sonography on women with PCO.
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http://dx.doi.org/10.1159/000052909 | DOI Listing |
Biol Open
December 2024
Department of Pathophysiology, School of Basic Medical Sciences, Anhui Medical University, Hefei 230032, China.
Epithelial to mesenchymal transition (EMT) has been shown to play an essential role in the early stages of cancer cell invasion and metastasis. Inducible EMT models can initiate EMT in a controlled manner, thereby providing the opportunity to determine whether a cancer-associated gene influences cancer metastasis by triggering EMT. Moreover, different inducible EMT models enable the investigation of specific mechanisms of EMT modulation by various genes, facilitating a more precise understanding of how these genes influence cancer metastasis through the induction of EMT.
View Article and Find Full Text PDFBMC Endocr Disord
September 2024
Jiangsu University Affiliated Hospital Thyroid and Breast Surgery Department, Zhenjiang, China.
Background: Parathyroid adenoma is the primary cause of primary hyperparathyroidism, commonly presenting with elevated parathyroid hormone (PTH) and blood calcium levels. Chronic primary hyperparathyroidism often results in bone destruction, resulting in the formation of brown tumors. The preferred clinical treatment for parathyroid adenoma is parathyroidectomy.
View Article and Find Full Text PDFWest Afr J Med
May 2024
Department of Surgery, University of Benin Teaching Hospital, Benin City, Nigeria. Phone number- +2348037214386; E-mail-
Background: Mammography has become an invaluable tool for diagnosing breast lesions and detecting early breast cancer in women of 35 years and above.
Aims: To correlate the mammography Breast Imaging Reporting and Data System (BI-RADS) categories with the histology in breast lesions and to determine the predictive values, sensitivity, specificity and accuracy of mammography.
Patients And Method: This was a one- year prospective study carried out from March 2015 to February 2016.
J Clin Ultrasound
November 2024
Department of Electrodiagnosis, Jilin Province FAW General Hospital, Changchun, China.
This systematic review and meta-analysis study aimed to determine the total capacity of contrast-enhanced ultrasound (CEUS) in the differential diagnosis of breast lesions and breast cancer. For collecting papers, four groups of keywords were searched in five databases. The required information was extracted from the selected papers.
View Article and Find Full Text PDFWomens Health (Lond)
July 2024
Division of Gynecology, Department of Surgery, Boston Children's Hospital, Boston, MA, USA.
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