Aim: To study nervous systems in chronic adrenal failure (CAF).

Material And Methods: 262 patients with CAF were studied clinically, biochemically and electrophysiologically before and after treatment.

Results: The patients were found to have syndromes of vegetovascular dystonia by hypotonic type, syncopal paroxysms, myastenic, minor strokes, dyscirculatory-dysmetabolic encephalopathy, polyneuropathy. A direct correlation was established between the severity and duration of adrenal failure (AF), lowering of adrenal cortex hormones, coefficient Na/K and clinical manifestations of the neurological syndromes. Adequate hormone replacing and symptomatic therapy promoted a regress of neurological disorders in most of the patients especially in mild and moderate AF.

Conclusion: Adequate therapy corrects neurological disturbances in patients with chronic NN.

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