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Oxyclozanide (OXY) is an anthelmintic widely used in the treatment of flatworm infection and fasciolosis. It also has antiadenovirus, antibiofilm, antifungal, and antibacterial activities. Various chemicals have been suggested as alternative chemicals in insect pest management.

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In the 1980s, a mass die-off of the long-spined sea urchin Diadema antillarum occurred on Florida and Caribbean coral reefs. D. antillarum populations largely did not recover, and in 2022, remaining populations experienced another mass mortality event.

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Optimization and validation of high-performance liquid chromatography using modified QuEChERS to determine anthelmintic drugs in mutton.

Biomed Chromatogr

March 2024

Department of Food Science and Quality Control, College of Agricultural Engineering Sciences, University of Sulaimani, Awall Street, Bakrajo, Bakrajo Campus, Sulaymaniyah, Kurdistan Region, Iraq.

The aim of this study was to rapidly determine the presence of anthelmintic drugs in sheep meat using the optimized high-performance liquid chromatography-ultraviolet (HPLC-UV) method with modified QuEChERS (quick, easy, cheap, effective, rugged, safe) technology. Fifty fresh sheep meat samples from different slaughterhouses were collected. A double extraction procedure (QuEChERS/HPLC-UV technology) was used to extract the target analytes.

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Based on the research strategy of "drug repurposing", a series of derivatives and marketed drugs that containing salicylic acid skeleton were tested for their antibacterial activities against phytopathogens. Salicylic acid can not only regulate some important growth metabolism of plants, but also induce plant disease resistance. The bioassay results showed that the salicylamides exhibited excellent antibacterial activity.

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Article Synopsis
  • Knowsley Safari conducted a coprological survey in June 2021 to check for liver fluke infections in 330 fecal samples from 18 exotic ungulate species, focusing particularly on vicuñas.
  • The survey found fascioliasis in all five vicuñas, and while the first treatment was inconclusive, a second treatment with triclabendazole proved effective.
  • To improve fluke management in the future, the study recommends regular fecal and snail monitoring, along with timely treatment when necessary.
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