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Sprouting sympathetic fibres release CXCL16 and norepinephrine to synergistically mediate sensory neuronal hyperexcitability in a rodent model of neuropathic pain.
Br J Anaesth
January 2025
Department of Anesthesiology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China. Electronic address:
Background: Chronic neuropathic pain generally has a poor response to treatment with conventional drugs. Sympathectomy can alleviate neuropathic pain in some patients, suggesting that abnormal sympathetic-somatosensory signaling interactions might underlie some forms of neuropathic pain. The molecular mechanisms underlying sympathetic-somatosensory interactions in neuropathic pain remain obscure.
View Article and Find Full Text PDFThe CT-Imaging Location of Lumbar 3 Sympathetic Radiofrequency Thermocoagulation for Sympathetic-Related Diseases Therapy.
J Pain Res
November 2024
Department of Anesthesiology and Pain Medicine, Affiliated Hospital of Jiaxing University, Jiaxing, People's Republic of China.
Purpose: The location characteristic of the lumbar 3 sympathetic trunk under Computed Tomography (CT) was discovered through 106 cases, imaging analysis after successful lumbar 3 sympathetic radiofrequency thermocoagulation operations serving the clinic and reducing the operation time.
Methods: There are 113 patients underwent bilateral L3 lumbar sympathetic thermal radiofrequency procedures in our hospital from January 2017 to January 2021, with 106 cases of successful procedure. Four operation image distances were measured: 1.
Laparoscopic versus open lumbar sympathectomy in critical limb threatening ischemia patients in Egypt.
BMC Surg
November 2024
General Surgery Department, Alexandria University, Faculty of Medicine, Alexandria, Egypt.
Article Synopsis
- - The study investigates the effectiveness of retroperitoneoscopic lumbar sympathectomy (RPLS) versus conventional open lumbar sympathectomy (COLS) for treating critical limb-threatening ischemia (CLTI) in patients who cannot undergo revascularization.
- - Patients who underwent RPLS experienced shorter hospital stays, fewer complications, and less postoperative pain, although the procedure took longer to perform initially.
- - The quality of life significantly improved in the RPLS group, with SF-36 scores rising notably, while no significant differences were found in other clinical measures between the two groups. RPLS is considered safe and effective but requires training to minimize operative time.
Sexual effects and long-term outcomes of endoscopic lumbar sympathectomy for plantar hyperhidrosis in men: a cross-sectional study.
J Vasc Bras
September 2024
Hospital Nossa Senhora das Graças - HNSG, Curitiba, PR, Brasil.
Article Synopsis
- Plantar hyperhidrosis (PHH) significantly affects psychosocial well-being, and endoscopic lumbar sympathectomy (ELS) is considered the best treatment option, despite concerns about compensatory sweating and sexual effects, especially in men.
- A study involving male patients who underwent ELS from 2014-2022 assessed the long-term effectiveness of the procedure and any postoperative side effects through remote interviews and standardized questionnaires.
- Results showed that 80% of patients achieved significant sweat reduction, with most reporting minimal issues related to compensatory sweating and no cases of erectile dysfunction, leading to improved quality of life and overall satisfaction with the surgery.
Article Synopsis
- The study looked at how many people got hospital treatment for a type of surgery called sympathectomy in Brazil from 2014 to 2023.
- It found that fewer people were having these surgeries over the years and that video-assisted surgeries were more common for chest operations but less for lower back ones.
- Even though video-assisted surgeries were safer, many still chose the older open surgery method, especially for lower back surgeries.
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