Several compounds designed as bisubstrate analogues of protein farnesyltransferase inhibited the prenyl protein-specific protease Rce1, qualifying them as lead structures for a novel class of non-peptidic, non-prenylic inhibitors of this protease.
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| http://dx.doi.org/10.1016/s0960-894x(00)00685-5 | DOI Listing |
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