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Background: Narcolepsy is a chronic disorder that requires lifelong management; however, few studies have evaluated disease burden of narcolepsy. We estimated the healthcare burden of narcolepsy in Japan using data from the Japan Medical Data Center health insurance claims database.
Methods: This was a retrospective analysis of clinical burden, healthcare resource utilization, and costs among incident narcolepsy cases and matched controls identified between January 1, 2014 and December 31, 2019.
Changes in Self-Directed Learning Among Doctor of Physical Therapy Students Across Didactic Curriculum: A Mixed-Methods Analysis.
J Phys Ther Educ
January 2025
Emily N. Getz is the director of outpatient therapy services and doctor of science in physical therapy program at the Bellin College, 3201 Easton Rd, Green Bay, WI Please address all correspondence to Emily N. Getz.
Introduction: Physical therapy education best practice includes the development of adaptive lifelong learners because of a constantly changing health care landscape. The purpose of this study was to identify how self-directed learning (SDL) changes in traditional Doctor of Physical Therapy (DPT) students over the course of the didactic curriculum.
Review Of Literature: The Master Adaptive Learning (MAL) framework has been proposed as a framework that physical therapy educators adopt to create and educate physical therapists who embrace continuous change and build a culture of creativity and innovation.
Living with Pediatric Coeliac Disease: Lessons for Health Service Delivery.
Dig Dis Sci
January 2025
Department of Paediatric Gastroenterology, Hepatology and Liver Transplant, Queensland Children's Hospital, Graham St, South Brisbane, 4101, Australia.
Background: Coeliac Disease (CD) affects up to 1.4% of children worldwide, with a rising global incidence. A less typical clinical presentation and the need for a life-long gluten exclusion diet raise challenges for diagnosis, management, and healthcare delivery with considerable impacts for CD patients and families as well as clinical services.
View Article and Find Full Text PDFUnveiling the influences of prenatal and maternal factors on the journey of an autistic child.
Front Psychiatry
December 2024
Department of Public Health and Community Medicine, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
Background: Autism Spectrum Disorder (ASD) is a complex lifelong neurodevelopmental disorder with a high and increasing global prevalence. Although the precise causes are unknown, both genetic and environmental factors, including maternal ones during pregnancy, significantly influence its development. Therefore, this study endeavors to explore the potential causes of autism, including maternal and paternal prenatal risk factors, as well as antenatal and natal maternal risk factors, and their associations with the severity of ASD in mothers of children with ASD, from February to May 2024.
View Article and Find Full Text PDFThe molecular mechanisms of cardiac development and related diseases.
Signal Transduct Target Ther
December 2024
Department of Cardiology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Cardiac development is a complex and intricate process involving numerous molecular signals and pathways. Researchers have explored cardiac development through a long journey, starting with early studies observing morphological changes and progressing to the exploration of molecular mechanisms using various molecular biology methods. Currently, advancements in stem cell technology and sequencing technology, such as the generation of human pluripotent stem cells and cardiac organoids, multi-omics sequencing, and artificial intelligence (AI) technology, have enabled researchers to understand the molecular mechanisms of cardiac development better.
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