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Extracellular acyl-CoA-binding protein as an independent biomarker of COVID-19 disease severity.
Front Immunol
January 2025
Inflammation and Immunity in Global Health Program, Research Institute of the McGill University Health Centre, Montreal, QC, Canada.
Background: Factors leading to severe COVID-19 remain partially known. New biomarkers predicting COVID-19 severity that are also causally involved in disease pathogenesis could improve patient management and contribute to the development of innovative therapies. Autophagy, a cytosolic structure degradation pathway is involved in the maintenance of cellular homeostasis, degradation of intracellular pathogens and generation of energy for immune responses.
View Article and Find Full Text PDFClinicians' Experiences of Eating Disorder Focused Family Therapy With Autistic Young People.
Eur Eat Disord Rev
January 2025
Department of Clinical & Health Psychology, University of Edinburgh, Edinburgh, UK.
Objective: Eating disorder focused family therapy (FT-ED) is the leading outpatient intervention for adolescents with Anorexia Nervosa. Autistic people report poorer eating disorder treatment experiences and may be at increased risk of inpatient admissions. There is a need to consider adaptions to eating disorder treatment for this population.
View Article and Find Full Text PDF[EFFICACY AND SAFETY OF ENFORTUMAB VEDOTIN IN ADVANCED UROTHELIAL CARCINOMA TREATMENT: AN INITIAL EXPERIENCE IN A SINGLE INSTITUTION].
Nihon Hinyokika Gakkai Zasshi
January 2025
Department of Urology, Kurume University School of Medicine.
(Purpose) Enfortumab vedotin has been available as a third-line treatment for advanced urothelial carcinoma in Japan since December 2021. While the treatment is expected to improve the outcome of advanced urothelial carcinoma, concerns regarding adverse events do exist. We report here our initial experience of the use of enfortumab vedotin as a third-line therapy in patients with advanced urothelial carcinoma.
View Article and Find Full Text PDF[The iatrogenic risk of institutional care in the management of patients with anorexia nervosa].
Soins
January 2025
Institut des sciences humaines en médecine, centre hospitalier universitaire vaudois, Université de Lausanne, avenue de Provence 82, 1007 Lausanne, Suisse; Laboratoire de psychologie clinique, psychopathologie, psychanalyse, École doctorale 261, Université Paris Cité, 71 avenue Édouard-Vaillant, 92100 Boulogne-Billancourt, France; Psychiatrie du développement et trajectoires, Inserm U1018, CESP, Hôpital Cochin, Maison de Solenn, 97 boulevard de Port-Royal, 75014 Paris, France. Electronic address:
This article explores the potential iatrogenic impact of institutional care on patients suffering from anorexia nervosa, based on a perspective drawn from the human and social sciences. In particular, it highlights the social mechanisms - such as the collision of intentions, pathological emulation, stigmatization and identity dedifferentiation - that can aggravate pathology in the hospital setting. Four recommendations are put forward for rethinking care, favoring a more holistic and less iatrogenic approach.
View Article and Find Full Text PDFRedefining diagnostic parameters: the role of overvaluation of shape and weight in binge-eating disorder: a systematic review.
J Eat Disord
January 2025
GGZ Rivierduinen Eating Disorders Ursula, Sandifortdreef 19, 2333 AK, Leiden, The Netherlands.
Introduction: Overvaluation of shape and weight is a critical component in understanding and diagnosing eating disorders. While the transdiagnostic model states that overvaluation of shape and weight is the core pathology of all eating disorders, this concept is not a criterion for binge-eating disorder. The lack of recognition of overvaluation of shape and weight may lead to overlooking, and consequently failure to address this construct during treatment.
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