The Free-Wilson equations are derived for the case of symmetrical substitution and are applied, in four modifications, to in vitro inhibitory activity of 77 organic disulfides against Histoplasma capsulatum. Substituent constants are listed to aid in the design of new inhibitory agents against this human pathogen (and perhaps other fungal organisms).
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Disentangling activity-stability trade-off in the catalytic degradation of malodorous sulfur-containing VOCs driven by active sites' self-dynamic evolution.
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