Temporal discrimination by healthy young and senior adults and patients with senile dementia was studied using the measure of transmitted information and two psychophysical methods (single-stimulus-ranking and pair-comparison). The patients with senile dementia showed very severe impairment on both methods and performed much less efficiently than the healthy adults of the same age; thus the former revealed a deficit in both memory and discrimination. The healthy seniors showed less alteration of temporal judgment with significant loss only with the single-stimulus method, which reflects memory deficit alone. Temporal cognition is very sensitive to changes in brain function.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1093/geronj/30.3.326 | DOI Listing |
PLoS One
January 2025
Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou, Jiangsu, PR. China.
Objectives: The aim of this study was to develop and validate a nomogram model that predicts the risk of bone metastasis (BM) in a prostate cancer (PCa) population.
Methods: We retrospectively collected and analyzed the clinical data of patients with pathologic diagnosis of PCa from January 1, 2013 to December 31, 2022 in two hospitals in Yangzhou, China. Patients from the Affiliated Hospital of Yangzhou University were divided into a training set and patients from the Affiliated Clinical College of Traditional Chinese Medicine of Yangzhou University were divided into a validation set.
Med J Armed Forces India
July 2024
Air Officer Commanding, 5 Air Force Hospital, Jorhat, India.
A 65-year-old male patient presented to eye outpatient department of a zonal hospital in North Eastern India with complaints of diminution of vision for 1-year duration. On ocular examination, his unaided visual acuity was 6/36 right eye and 6/12 left eye. He was diagnosed as a case of immature senile cataract with nuclear sclerosis grade 2+ in the right eye and immature senile cataract with nuclear sclerosis grade 1+ in the left eye, with no other ocular or systemic findings.
View Article and Find Full Text PDFFront Immunol
January 2025
Acupuncture and Moxibustion College, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
Introduction: Ulcerative colitis (UC) is a chronic inflammatory disease. Patients with UC typically exhibit disruption of the Treg/Th17 immune axis, but its exact mechanism is still unclear.
Methods: This study first analyzed RNA- seq data from public databases of humans and mice, and cytology experiments were conducted to induce or inhibit the expression of SIRT1.
Eye Contact Lens
January 2025
Department of Ophthalmology (O.O.), Niğde Ömer Halisdemir University, Niğde, Turkey; Department of Ophthalmology (O.D.), Mersin University, Mersin, Turkey; Department of Ophthalmology (P.E.), Tarsus State Hospital, Mersin, Turkey; and Department of Ophthalmology (E.S.G.), Mersin State Hospital, Mersin, Turkey.
Objectives: To investigate the effect of cataract surgery on visual acuity, stereoacuity, balance, and falls in patients with senile cataract.
Methods: Prospective, cross-sectional study. The patients were divided into group 1 if the first surgery was performed on the dominant eye and group 2 on the nondominant eye.
J Nanobiotechnology
January 2025
Shanghai Key Laboratory of Orthopaedic Implants, Department of Orthopaedic Surgery, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, 639 Zhizaoju Road, Shanghai, 200011, P.R. China.
Background: Osteoarthritis (OA) is a degenerative joint disease with an immense unmet medical need. FGF18 protein is a potential regenerative factor for cartilage repair. However, traditional protein delivery methods have limited efficacy due to the short lifetime and shallow infiltration.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!