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Detection of Extracochlear Electrodes Using Electrical Field Imaging (EFI).
Otol Neurotol
February 2025
Department of Otolaryngology-Head and Neck Surgery, Mayo Clinic, Rochester, Minnesota.
Objective: To analyze the use of electrical field imaging (EFI) in the detection of extracochlear electrodes in cochlear implants (CI).
Study Design: Retrospective cohort study.
Setting: Tertiary academic medical center.
Asymmetric Synthesis and Biological Evaluation of Both Enantiomers of 5- and 6-Boronotryptophan as Potential Boron Delivery Agents for Boron Neutron Capture Therapy.
ACS Med Chem Lett
December 2024
School of Pharmacy, University of Eastern Finland, P.O. Box 1627, FI-70211 Kuopio, Finland.
This research investigates boronated tryptophans as potential boron delivery agents for boron neutron capture therapy (BNCT) of cancer. We synthesized both enantiomers of 5- and 6-boronotryptophans ( and ) using simple and inexpensive methods. Their uptake was assessed in two human cancer cell lines, CAL27 (head and neck cancer) and U87-MG (brain cancer), and compared to l--boronophenylalanine (l-BPA) as a reference.
View Article and Find Full Text PDFThe added value of narrow band imaging in Sinonasal tumour resection and surveillance: Our experience.
Am J Otolaryngol
December 2024
ENT Department, University Hospitals Plymouth NHS Trust, Plymouth, UK; Peninsula Medical School, University of Plymouth, Plymouth, UK.
Background & Purpose: Narrow Band Imaging (NBI), developed by Olympus Medical Systems, has played a role in diagnosing digestive tract lesions and cancers, diagnosing and characterizing bladder cancers during cystoscopy and in the diagnosis and management of Head and Neck cancers. We aim to explore the potential use of NBI in the diagnosis, management, and follow-up of sinonasal tumours.
Methods: We present a series of cases treated at our institution, where NBI played a crucial role in the diagnosis, surgical management, intraoperative decision-making, and follow-up.
Peripheral perfusion response to semiorthostatic stress: a simple method for assessing autonomic dysfunction in sepsis?
Crit Care Sci
December 2024
Intensive Care Unit, Hospital de Clínicas, Universidade Federal do Paraná - Curitiba (PR), Brazil.
Article Synopsis
- The study aimed to assess how the perfusion index (PI) response to a specific stress test can indicate sympathetic-vascular reactions in patients with sepsis compared to healthy individuals and critically ill patients without sepsis.
- Three groups were analyzed: healthy patients (Group A), critically ill patients without sepsis (Group B), and septic patients (Group C), focusing on their hemodynamic responses and changes in the perfusion index during a semiorthostatic stress test.
- Findings showed that healthy individuals exhibited expected changes in cardiac function, while septic patients displayed variable responses; notably, those with a decreased perfusion index after the test had better outcomes (lower SOFA scores) after 72 hours, suggesting that monitoring the PI may
Introduction: Various techniques have been described for restoring leg length and offset during total hip arthroplasty (THA). We herein describe a novel "Quartered Head Technique" (QHT) involving a series of femoral osteotomies.
Methods: 124 hips were included in the analysis.
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