AI Article Synopsis
- A new compound called epidioxysterol has been isolated from the tunicate Cynthia savignyi, marking the first time this compound has been found in this species.
- The structure of epidioxysterol was characterized using advanced NMR techniques, including 1H, 13C, and 2D NMR.
- This compound shows promising biological activities, exhibiting antifungal effects against three types of pathogenic fungi, antibacterial activity against several bacteria, and cytotoxicity against brine shrimp larvae.
Article Abstract
From a hexane extract of the tunicate Cynthia savignyi, collected in Morocco, epidioxysterol or 5,8-alpha-epidioxy-5alpha-cholest-6-en-3beta-ol has been isolated. This is the first example of epidioxysterol found in the tunicate C. savignyi. The structure of epidioxysterol has been characterised by NMR data (1H, 13C and 2D). Epidioxysterol possesses antifungal activity against three tomato pathogenic fungi: Botrytis cinerea, Fusarium oxysporum and Verticillium albo atrum and antibacterial activity against Agrobacterium tumefaciens, Escherichia coli, Staphylococcusfaecalis, Staphylococcus aureus and Pseudomonas aeruginosa and cytotoxicity against Artemia salina larvae.
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| http://dx.doi.org/10.1016/s0014-827x(00)00040-9 | DOI Listing |
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