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Research Funded by National Institutes of Health Concerning Sexual and Gender Minoritized Populations: A Tracking Update for 2012 to 2022.
Am J Public Health
January 2025
Ben C. D. Weideman, Alexandra M. Ecklund, Rhea Alley, and B. R. Simon Rosser are with the Division of Epidemiology & Community Health, School of Public Health, University of Minnesota, Minneapolis. G. Nic Rider is with the Eli Coleman Institute for Sexual and Gender Health, Department of Family Medicine and Community Health, University of Minnesota Medical School, Minneapolis.
To investigate trends in awards funded by the National Institutes of Health (NIH) focusing on sexual and gender minoritized (SGM) populations from 2012 to 2022 in the United States. Replicating the method of Coulter et al., we identified NIH-funded awards for SGM research from 2012 to 2022 using the NIH RePORTER (Research Portfolio Online Reporting Tools Expenditures and Results) system.
View Article and Find Full Text PDFPrevalence, impact and management strategies for dysmenorrhea in Aotearoa New Zealand: a scoping review.
N Z Med J
January 2025
Associate Professor, NICM Health Research Institute, Western Sydney University, Sydney, Australia; Honorary Research Fellow, Medical Research Institute of New Zealand, Wellington, New Zealand.
Background And Aim: Dysmenorrhea affects the majority of young women worldwide, but geographical and cultural differences can influence the reporting, impact and management of symptoms. Aotearoa New Zealand is a culturally diverse country, with a high proportion of Māori and Pacific peoples. The aim of this scoping review was to assess the current literature on the prevalence, impact and management strategies for dysmenorrhea in Aotearoa New Zealand.
View Article and Find Full Text PDFEffectiveness of Oral Prophylactic Antibiotics for Diagnostic Bronchoscopy: A Nationwide Database Study.
Ann Am Thorac Soc
January 2025
The University of Tokyo, Department of Clinical Epidemiology and Health Economics, Bunkyo-ku, Tokyo, Japan.
Rationale: Although the guidelines generally omit routine antibiotic prophylaxis for diagnostic bronchoscopy, this recommendation is primarily based on studies with relatively small sample sizes conducted at single institutions. Moreover, the applicability of recent technical and procedural advancements to these guidelines remains uncertain.
Objectives: To evaluate whether oral prophylactic antibiotic administration for diagnostic bronchoscopy reduces post-bronchoscopy infections among non-infectious diseases in the current setting.
A longitudinal analysis of neurocognitive profiles in South African women with HIV.
AIDS Care
January 2025
South African Medical Research Council / Stellenbosch University Genomics of Brain Disorders Research Unit, Department of Psychiatry, Stellenbosch University, Cape Town, South Africa.
HIV and the consequences of HIV-associated neurocognitive disorders (HAND) disproportionally affect South African women. Longitudinal neurocognitive data on women with HIV are limited. We tracked longitudinal neurocognitive profiles of South African women with HIV (baseline = 140) compared to women without HIV (baseline = 156).
View Article and Find Full Text PDFLysosomal dysfunction and inflammatory sterol metabolism in pulmonary arterial hypertension.
Science
January 2025
Center for Pulmonary Vascular Biology and Medicine, Pittsburgh, Heart, Lung, and Blood Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA, USA.
Vascular inflammation regulates endothelial pathophenotypes, particularly in pulmonary arterial hypertension (PAH). Dysregulated lysosomal activity and cholesterol metabolism activate pathogenic inflammation, but their relevance to PAH is unclear. Nuclear receptor coactivator 7 () deficiency in endothelium produced an oxysterol and bile acid signature through lysosomal dysregulation, promoting endothelial pathophenotypes.
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