Purpose: To determine the estimated absorbed ovarian dose (EAOD) and absorbed skin dose (ASD) that occurs during uterine artery embolization (UAE) using pulsed fluoroscopy and a refined procedure protocol.
Materials And Methods: The absorbed dose was measured in 20 patients who underwent UAE procedures. Radiation was limited by using low frequency pulsed fluoroscopy, bilateral catheter technique with simultaneous injections for embolization as well as pre-and postembolization exposures and focus on limitation of magnified and oblique fluoroscopy. Lithium fluoride dosimeters were placed both in the posterior vaginal fornix and on the skin at the beam entrance site. The vaginal dose was used to approximate the EAOD. Fluoroscopy time and exposures were recorded. The mean values for all patients were calculated and compared to our previous results obtained with conventional fluoroscopy and to threshold doses for the induction of deterministic skin injury.
Results: Mean fluoroscopy time was 10.95 min. (range 6-21.3 min.) and the mean number of angiographic exposures was 20.9 (range 14-53). The mean EAOD was 9.5 cGy (range 2.21-23.21 cGy) and the mean ASD was 47.69 cGy (range 10.83-110.14 cGy). This compares to previous results with non-pulsed fluoroscopy of an EAOD of 22.34 cGy (range 4.25-65.08 cGy) and an ASD of 162.32 cGy (range 66.01-303.89 cGy) as well as threshold doses for induction of deterministic radiation injury to the skin (400-500 cGy).
Conclusion: When pulsed fluoroscopy is used with emphasis on dose reduction techniques, the EAOD and ASD can be substantially reduced to less than 1/2 (P = .017) and 1/3 (P < .0001) when compared to UAE performed with nonpulsed fluoroscopy. These radiation reduction tools should therefore be applied whenever possible.
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http://dx.doi.org/10.1016/s1051-0443(07)61400-6 | DOI Listing |
Radiother Oncol
January 2025
Department of Radiation Oncology, Medical College of Wisconsin, Milwaukee, WI 53226, United States. Electronic address:
Background: Re-irradiation in radiotherapy presents complexities that require dedicated tools to generate optimal re-treatment plans. This study presents a robust workflow that considers fractionation size, anatomical variations between treatments, and cumulative bias doses to improve the re-irradiation planning process.
Methods: The workflow was automated in MIM® Software and the Elekta© Monaco® treatment planning system.
Ann Palliat Med
November 2024
Radiation Medicine Program, The Ottawa Hospital/University of Ottawa, Ottawa, ON, Canada.
Background: Palliative radiotherapy (RT) is commonly used for malignancy-associated hemoptysis. This study aims to determine RT control probability, durability, and influencing factors.
Methods: This single-institution prospective observational study included patients ≥18 years old with any lung malignancy and active hemoptysis.
Adv Radiat Oncol
December 2024
Department of Radiation Oncology, University of Colorado Cancer Center, Aurora, Colorado.
Purpose: Patients with metastatic castrate-resistant prostate cancer (CRPC) with progressive disease generally require a change or escalation in systemic therapy. For patients with limited (1-3) sites of progressive disease (oligoprogression), metastasis-directed therapy with stereotactic body radiation therapy (SBRT) may allow a longer interval before next-line systemic therapy.
Methods And Materials: This is a retrospective study of patients with oligoprogressive metastatic CRPC (mCRPC) treated with SBRT at a single center between 2011 and 2022.
Transplant Cell Ther
January 2025
Division of Hematology & HSCT, Department of Oncology, King Abdulaziz Medical City, Ministry of National Guards-Health Affairs, Riyadh, Saudi Arabia; King Abdullah International Medical Research Center, Riyadh, Saudi Arabia; College of Medicine, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia; Saudi Scientific Society of Blood and Marrow Transplantation, Jeddah, Saudi Arabia. Electronic address:
Biomed Phys Eng Express
November 2024
Department of Advanced Radiation Oncology and Proton Therapy, Inova Schar Cancer Institute, VA, United States of America.
. We aim to characterize kinetics of radiation-induced optical density in newly released EBT4 radiochromic films exposed to clinical x-rays. Several film models and batches were evaluated for the film sensitivity, optical signal increasing with time, relative film noise, and minimum detectable limits (MDL).
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