Predicting electrospray response from chromatographic retention time.

Anal Chem

Department of Chemistry, The University of New Mexico, Albuquerque 87131-1096, USA.

Published: January 2001

The relationship between electrospray ionization response and HPLC retention time was explored. For the series of small peptides studied, higher ESI response was observed for analytes with longer reversed-phase HPLC retention times. This correlation existed for both experimentally measured retention times and those calculated from amino acid retention coefficients. This study is useful t

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Source
http://dx.doi.org/10.1021/ac0006019DOI Listing

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