Morphological and morphometrical study is performed on serial and stepped sections of the lungs surgically removed from patients with bronchoectatic disease. As compared to healthy persons, hyperplasia of all structural components with formation of lymphoid and lymphoepithelial follicles was detected. The degree of lymphoid tissue hyperplasia in bronchoectatic disease is determined by inflammation activity and does not depend on the age. The number of interepithelial lymphocytes is significantly increased as well as that of peribronchial and peribronchiolar lymphoid accumulations, and the degree of diffuse infiltration. However, the number of periglandular and periductal lymphoid accumulations and lymphoid follicles is significantly reduced. Bronchoectatic disease with high active inflammation as compared to low activity is characterized by more pronounced hyperplasia with formation of lymphoid and lymphoepithelial follicles with clear centers.
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