We propose the use of anisotropic diffusion filtering to remedy difficulties in analysis of electronic portal images, stemming from their low contrast and high noise levels. Anisotropic diffusion is a nonlinear filter based on the numerical solution to the partial differential equation describing the process of diffusion. In this study we show that this filter is capable of greatly reducing noise in homogeneous areas of portal images while preserving the edges and contrast associated with anatomical features. We also demonstrate that the application of anisotropic diffusion leads to more consistent and reproducible visual extraction of features from portal images.
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http://dx.doi.org/10.1088/0031-9155/46/1/318 | DOI Listing |
Int J Biol Macromol
January 2025
State Key Laboratory of Inorganic Synthesis and Preparative Chemistry, Jilin University, 2699 Qianjin Street, Changchun 130012, PR China. Electronic address:
Multidirectional strain sensors are of technological importance for wearable devices and soft robots. Here, we report that flexible materials capable of multidirectional anisotropic strain sensing can be constructed leveraging diffusion-induced infiltration of monomers and in situ polymerization of metal ion-containing double network hydrogels in and on the surface of micro-corrugated chiral nematic cellulose nanocrystal/glucose films. Integrating the micro-corrugated cellulose nanocrystal/glucose chiral nematic films with ionic conductive hydrogels of PAA-co-AAm/sodium alginate/Al endows the materials with multidirectional mechanoelectrical resistivity and mechanochromism anisotropy.
View Article and Find Full Text PDFSci Adv
January 2025
Interdisciplinary Graduate School of Engineering Sciences, Kyushu University, Fukuoka 816-8580, Japan.
Transition metal dichalcogenides (TMDs) exhibit unique properties and potential applications when reduced to one-dimensional (1D) nanoribbons (NRs), owing to quantum confinement and high edge densities. However, effective growth methods for self-aligned TMD NRs are still lacking. We demonstrate a versatile approach for lattice-guided growth of dense, aligned MoS NR arrays via chemical vapor deposition (CVD) on anisotropic sapphire substrates, without tailored surface steps.
View Article and Find Full Text PDFPharmaceutics
December 2024
Wits Advanced Drug Delivery Platform, Department of Pharmacy and Pharmacology, School of Therapeutic Sciences, Faculty of Health Sciences, University of the Witwatersrand, 7 York Road, Parktown, Johannesburg 2193, South Africa.
The effectiveness of paclitaxel (PTX) in treating non-small-cell lung carcinoma (NSCLC) is restricted by its poor pharmacokinetic profile and side effects. This limitation stems from the lack of a suitable delivery vector to efficiently target cancer cells. Therefore, there is a critical need to develop an efficient carrier for the optimised delivery of PTX in NSCLC therapy.
View Article and Find Full Text PDFUnlabelled: Evaluating tissue microstructure and membrane integrity in the living human brain through diffusion-water exchange imaging is challenging due to requirements for a high signal-to-noise ratio and short diffusion times dictated by relatively fast exchange processes. The goal of this work was to demonstrate the feasibility of imaging of tissue micro-geometries and water exchange within the brain gray matter using the state-of-the-art Connectome 2.0 scanner equipped with an ultra-high-performance gradient system (maximum gradient strength=500 mT/m, maximum slew rate=600 T/m/s).
View Article and Find Full Text PDFPhys Chem Chem Phys
January 2025
Helmholtz Institute Erlangen-Nürnberg for Renewable Energy, Forschungszentrum Jülich, Fürther Strasse 248, 90429 Nürnberg, Germany.
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