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Seroprevalence of Hepatitis B and C and HIV Infections and Associated Risk Factors Among Pregnant Women Attending Antenatal Care Unit at Simada Hospital, South Gondar Zone, Northwest Ethiopia.
Biomed Res Int
January 2025
Department of Biology, College of Natural & Computational Sciences, University of Gondar, Gondar, Ethiopia.
Hepatitis and human immunodeficiency virus (HIV) are major public health issues in developing countries, including Ethiopia. These viruses can be transmitted from mother to child during birth or through contact with contaminated blood. In many areas of Ethiopia, viral hepatitis and HIV infections are significant health concerns for pregnant women.
View Article and Find Full Text PDFAlignment of countries in the Americas with the latest WHO guidelines for hepatitis B virus (HBV) infection: a review.
Lancet Reg Health Am
November 2024
Evandro Chagas National Institute of Infectious Diseases (INI), Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro, RJ, Brazil.
Evidence is lacking on alignment of current guidance from the Region of the Americas (AMR) countries with the new guidelines for people with hepatitis B virus (HBV) infection published by the World Health Organization (WHO) in March 2024. We gathered the most updated guidance on HBV infection from organisations/societies and seven countries from AMR. Most guidelines were aligned with the new WHO recommendation to treat persons with elevated ALT and HBV-DNA levels ≥2,000 IU/ml or with HIV-coinfection, hepatocellular carcinoma family history, extra-hepatic manifestations, or immunosuppression.
View Article and Find Full Text PDFRacial and Ethnic Disparities in Testing of Hepatitis C Virus-Exposed Children Across the United States.
J Pediatric Infect Dis Soc
November 2024
Department of Pediatrics, Section of Newborn Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA.
Background: Despite rising hepatitis C virus (HCV) prevalence among pregnant individuals in the United States, HCV testing among exposed infants remains low. Although recent guidelines recommend early ribonucleic acid (RNA) testing for HCV-exposed children to help improve testing rates, national studies describing factors associated with HCV testing and the type of testing completed are lacking.
Methods: In this retrospective national study, we characterized HCV testing and care among HCV-exposed infants born between 2010 and 2020 captured in the electronic health record-based TriNetX Research Network.
Screening for viral hepatitis carriage.
Best Pract Res Clin Obstet Gynaecol
September 2024
Departments of Laboratory Medicine and Infectious Diseases and Obstetrics & Gynecology, Nanjing Drum Tower Hospital, Nanjing University Medical School, Nanjing, China. Electronic address:
Viral hepatitis during pregnancy is common globally. In this review, we focus on the antenatal screen for hepatitis A, B, C and E, the prevention of mother-to-child transmission (MTCT) of hepatitis B and C, and the management of hepatitis A, B, C and E during pregnancy. Neonatal timely administration of hepatitis B immunoglobulin and hepatitis B vaccine is the cornerstone for preventing MTCT of hepatitis B virus (HBV), and perinatal antiviral prophylaxis with tenofovir disoproxil fumarate in mothers with positive HBeAg or HBV DNA >2 × 10 IU/ml also plays important roles in further reducing MTCT.
View Article and Find Full Text PDFArticle Synopsis
- Hepatitis B virus (HBV) and hepatitis delta virus (HDV) co-infection is severe and can be transmitted from mother to child, with significant rates found in pregnant women in Cameroon.
- A study involving 1992 pregnant women revealed a 6.7% prevalence of HBsAg, with 32.3% of HBsAg-positive women also being anti-HDV antibody-positive and almost half showing detectable HDV RNA levels.
- Risk factors linked to HDV presence included multiple pregnancies and body modifications like tattoos, highlighting the need for awareness and preventive measures against maternal transmission of HDV.
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