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Multicentric Cross-Sectional Survey to Assess the Variation of Fractionation Strategies Used in the Management of Head and Neck Cancers in the Asian Region (INNOCENCE-ASIA).
JCO Glob Oncol
January 2025
Department of Radiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Purpose: Head and neck cancers (HNCs) are in general treated with conventional fractionation regimen of 1.8-2 Gy per fraction. Altered fractionation (ALFT) strategies such as hypofractionation radiotherapy (HYPO-RT), accelerated fractionation radiotherapy (AFRT), and hyperfractionation radiotherapy (HFRT) have not been practiced uniformly across centers in different parts of the world.
View Article and Find Full Text PDFA qualitative systematic review of umbilical cord care practices in Nigeria.
BMC Pediatr
January 2025
Department of Public Health, Federal University of Technology Owerri, Owerri, Imo State, Nigeria.
Background: Umbilical cord care is an important aspect of newborn health, and different practices exist around the world, often influenced by cultural, healthcare infrastructure, and socioeconomic factors. The objective of this systematic review is to synthesize current literature on umbilical cord care practices in Nigeria, with an emphasis on the impact of cultural beliefs, healthcare infrastructure, and socioeconomic factors.
Methods: A comprehensive search for literature was performed across PubMED, MEDLINE and Google scholar for studies published between 2010 and 2023.
The Golgi complex governs natural killer cell lytic granule positioning to promote directionality in cytotoxicity.
Cell Rep
January 2025
Vagelos College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA. Electronic address:
Cytotoxic immune cells mediate precise attacks against diseased cells to maintain organismal health. Their operational unit of killing and host defense is lytic granules (LGs), which are specialized lysosomal-related organelles. Precision in cytotoxicity is achieved by converging the many LGs to the microtubule-organizing center (MTOC) and polarizing these to the diseased cell for secretion.
View Article and Find Full Text PDFOpioid use and abuse in adolescents and young adults; dealing with science, laws and ethics: Charming the COBRAS.
Dis Mon
January 2025
Department of Pediatric and Adolescent Medicine, Western Michigan University, Homer Stryker M.D. School of Medicine, Kalamazoo, MI, USA.
The subject of substance use disorders in the pediatric population remains a disturbing conundrum for clinicians, researchers and society in general. Many of our youth are at risk of being damaged and even killed by drug addictions that result from the collision of rapidly developing as well as vulnerable central nervous systems encountering the current global drug addiction crisis. A major motif of this chemical calamity is opioid use disorder in adolescents and young adults that was stimulated by the 19th century identification of such highly addictive drugs as morphine, heroin and a non-opiate, cocaine.
View Article and Find Full Text PDF2-Amidophenolate and 2-Iminosemiquinone Radical-Coordinated Vanadyl Complex as Catholyte for Non-Aqueous Redox-Flow Batteries.
Chem Asian J
January 2025
Indian Institute of Technology Guwahati, Department of Chemistry, Department of Chemistry, 781039, Guwahati, INDIA.
Fulfilment of energy demand by utilizing renewable energy sources that do not contribute to the production of greenhouse gases is a step forward in mitigating global warming. However, with the energy sources being intermittent in nature, renewable energy needs to be stored effectively on a grid scale. In this context, the development of redox-flow batteries has emerged as a promising technology where charging and discharging processes are accomplished by the redox shuttling of the electrolytes, namely anolytes and catholytes.
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