Structural-functional organisation of the cortical insular area relating to processes of the visceral functions control, was analysed. Representation of gastrointestinal, respiratory, and cardiovascular systems in the area, is given. Sites of respective neuronal groups and specifics of their spatial organisation within the area, were found. The data obtained suggest a scheme of the rat insular cortex's visceral field.
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Neurosci Lett
December 2024
Department of Anatomy, Koç University, School of Medicine, Istanbul, Turkey. Electronic address:
The insular cortex (ICx) has a role in large a variety of functions. Thalamus plays an important role in modulating cortical functions. The present study aims to show thalamic-ICx connections using the fluoro-gold (FG) tracing method in rats and diffusion tensoring-based tractography (DTI) in humans.
View Article and Find Full Text PDFBrain Behav
December 2024
Department of Hyperbaric Oxygen, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China.
Introduction: Spinal cord injury (SCI) can result in sensory and locomotor function loss below the injured segment. Hyperbaric oxygen therapy (HBOT) has been proven to alleviate SCI. This study aims to establish a reproducible rat model of SCI and investigate the impact of HBOT on alterations in brain neuronal activity and neuromotor function in this experimental rat SCI model using resting-state functional magnetic resonance imaging (rs-fMRI).
View Article and Find Full Text PDFiScience
December 2024
Laboratory Neurobiology of Appetite, Department of Pharmacology, Center for Research and Advanced Studies of the National Polytechnic Institute, Mexico City 07360, Mexico.
The gustatory system allows us to perceive and distinguish sweetness from water. We studied this phenomenon by recording neural activity in rats' anterior insular (aIC) and orbitofrontal (OFC) cortices while they categorized varying sucrose concentrations against water. Neurons in both aIC and OFC encoded the categorical distinction between sucrose and water rather than specific sucrose concentrations.
View Article and Find Full Text PDFNeurosci Lett
January 2025
Department of Psychological and Brain Sciences, Colgate University, Hamilton, NY, USA. Electronic address:
Prolonged periods of opioid use have been shown to cause neuroadaptations in the brain's reward circuitry, contributing to addictive behaviors and drug dependence. Recently, considerable focus has been placed on the role of the endocannabinoid system (ECS) and its CB receptors in opioid-driven behaviors. However, opioid-induced neuroadaptations to the ECS remain understudied.
View Article and Find Full Text PDFbioRxiv
October 2024
Neuroscience Curriculum, School of Medicine, University of North Carolina - Chapel Hill, Chapel Hill, NC.
Background: Traumatic stress is associated with high rates of problematic alcohol use, but how the persistent effects of trauma impact sensitivity to alcohol remain unknown. This study examined the persistent effects of traumatic stress exposure on sensitivity to alcohol and underlying neurobiological mechanisms in rats.
Methods: Male (N=98) and female (N=98) Long-Evans rats were exposed to the predator odor TMT, and two weeks later, molecular, neuronal, and behavioral sensitivity to alcohol were assessed.
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