Over a 10-year period, a total of 403 patients with mammary gland carcinoma--398 women (98.8%) and five men (1.2%)--are operated in the Clinic of Thoracic Surgery & Oncology at the Military Medical Academy. The mean age in men, as compared to that in women, is nearly 12 years older. In one patient tumorectomy is done for "cleanliness" on account of the seriously impaired general condition. In the remainder the operative intervention is radical mastectomy after Patey or Pirogov, with meticulous axillary lymph dissection. In all men operated on, gynecomastia concurrent to the underlying disease is found. The histological patterns of mammary gland cancer in male patients is identical to the histological picture in women.
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Front Nutr
January 2025
College of Animal Science and Technology, Henan Agricultural University, Zhengzhou, China.
Improving mammary gland epithelial cells proliferation through nutrition is an important approach for enhancing sow milk production and piglet growth. An intermediate metabolite of valine, 3-hydroxyisobutyrate (3-HIB), regulates cellular lipid metabolism. In the present study, we investigated the effects of 3-HIB on porcine mammary gland epithelial cells proliferation and lipid metabolism.
View Article and Find Full Text PDFMicroorganisms
January 2025
College of Veterinary Medicine, China Agricultural University, Beijing 100193, China.
Bovine mastitis, a prevalent disease in dairy farms, exerts a profound negative influence on both the health and productivity of dairy cattle, leading to substantial economic losses for the dairy industry. The disease is associated with different bacterial agents, primarily Gram-positive cocci (e.g.
View Article and Find Full Text PDFAnimals (Basel)
January 2025
Jiangsu Key Laboratory of Sericultural and Animal Biotechnology, School of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang 212100, China.
In periparturient dairy cows, high non-esterified fatty acids (NEFAs) caused by a severe negative energy balance induce oxidative stress and metabolic dysfunction, which pose a severe challenge to the dairy industry. Resveratrol (RES) is a polyphenolic compound with antioxidant, anti-inflammatory and multiple other physiological effects. However, its effect on oxidative damage triggered by NEFAs in bovine mammary epithelial cells is rarely reported.
View Article and Find Full Text PDFDiagnostics (Basel)
January 2025
School of Molecular Sciences, The University of Western Australia, Crawley, WA 6009, Australia.
The causes of low milk supply are multifactorial, including factors such as gene mutations, endocrine disorders, and infrequent milk removal. These factors affect the functional capacity of the mammary gland and, potentially, the concentrations of milk components. This study aimed to investigate the differences in milk composition between mothers with low and normal milk supply and develop predictive machine learning models for identifying low milk supply.
View Article and Find Full Text PDFRes Vet Sci
January 2025
Instituto Multidisciplinario de Investigación y Transferencia Agroalimentaria y Biotecnológica (IMITAB), CONICET-UNVM, Villa María, Córdoba, Argentina; Instituto Académico Pedagógico de Ciencias Básicas y Aplicadas de la Universidad Nacional Villa María (IAPCByA-UNVM), Villa María, Córdoba, Argentina. Electronic address:
The World Health Organization recently reported an alarming evolution and spread of antibiotic resistance, a global risk factor recognized as a One Health challenge. In veterinary, the general lack of clear treatment guidelines often leads to antibiotic misuse. Bovine mastitis is responsible for major economic losses and the main cause of antibiotic administration in the dairy industry, favoring the emergence of multi-resistant phenotypes.
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