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Serum gastrin concentrations were measured in 75 subjects of blood group O and in 75 subjects of other blood groups. Gastrinaemia both basally and following stimulation by glycine drink or by insulin hypoglycaemia did not show any statistically significant differenc in blood group O people as compared to subjects of other blood groups. It is concluded that the claimed relationship between blood group O and parietal cell hyperplasia cannot be considered as secondary to a relationship between blood group O and increased gastrin-producting G cell mass.
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