Ignorance is not bliss.

Nurs Times

Greater Glasgow Primary Care NHS Trust.

Published: March 2001

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  • The study investigates how access to air-related information and awareness of public policies influence citizens' life satisfaction, particularly in relation to their perceptions of air pollution sources.
  • It challenges the assumption that all individuals can readily access and interpret officially disclosed air quality information, highlighting a research gap regarding real-world information accessibility and its effects.
  • Analyzing data from 1867 Beijing residents, the findings indicate that both higher information accessibility and greater policy awareness lead to improved life satisfaction, with variations noted based on perceptions of air pollution.
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Ignorance is bliss: Inhibition of proteomic stress sensing improves direct neuronal conversion.

Neuron

April 2024

Department of Neurosciences, University of California San Diego, La Jolla, CA, USA; Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA; Laboratory of Genetics, The Salk Institute for Biological Studies, La Jolla, CA, USA. Electronic address:

Direct conversion of non-neuronal cells to neurons offers opportunities for disease modeling and therapy. In this issue of Neuron, Sonsalla et al. reveal the unfolded protein response (UPR) pathway as a "proteomic roadblock" to direct neuronal conversion; overcoming this roadblock enhances reprogramming.

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Background: Congenital Adrenal Hyperplasia (CAH) due to 21-hydroxylase deficiency (21HD) can affect the in utero development of the genital anatomy of people with the 46XX karyotype. Health professionals engage parents in decision-making regarding managing genitals with this difference, including genital surgery options and patient communication.

Aim: We sought to investigate parental communication with their daughters regarding clitoral size variation related to neonatal CAH.

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The polypill strategy, which combines several medicines that simultaneously control different risk factors/diseases in a single pill, is one of the approaches used in cardiovascular therapy. In different guidelines, this one-pill combination therapy is suggested as first-line step in disease management. Because the cardiovascular diseases (CVD) pandemia, prevention is essential.

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